Results 41 to 50 of about 77,523 (237)

Clusters of polymorphic transmembrane genes control resistance to schistosomes in snail vectors

open access: yeseLife, 2020
Schistosomiasis is a debilitating parasitic disease infecting hundreds of millions of people. Schistosomes use aquatic snails as intermediate hosts.
Jacob A Tennessen   +6 more
doaj   +1 more source

Niche Preference of Escherichia coli in a Peri-Urban Pond Ecosystem

open access: yesLife, 2021
Escherichia coli comprises diverse strains with a large accessory genome, indicating functional diversity and the ability to adapt to a range of niches.
Gitanjali NandaKafle   +5 more
doaj   +1 more source

A Comprehensive Review of Waste‐Derived Materials for Solar Still Performance Enhancement

open access: yesAdvanced Materials Interfaces, EarlyView.
ABSTRACT Solar desalination reduces energy use and produces freshwater sustainably, but its productivity is limited and cannot meet rising demand. Thus, solar desalination system improvements are sought to boost water productivity. Waste materials are abundantly available and burden the environment, making them low‐cost enhancers for solar desalination
A. S. Abdullah   +6 more
wiley   +1 more source

Diet of schistosome vectors influences infection outcomes

open access: yesEcosphere
Resource availability can alter infection outcomes through its impact on host immunity and on parasite reproduction. On one hand, enhanced nutrition could favor immunity, limiting the parasite, and on the other hand, it could favor establishment and ...
Joshua Trapp   +7 more
doaj   +1 more source

Dynamic Current Routing in Conductive Liquid Crystal Elastomers for Complex Deformation Actuators

open access: yesAdvanced Materials Technologies, EarlyView.
This work introduces a novel actuation control strategy in which electrical stimulation generates localized Joule heating in conductive liquid crystal elastomer (LCE) surfaces, enabling complex 3D deformations from a single homogeneous surface without preprogramming.
Gloria PouWai Lei   +2 more
wiley   +1 more source

Strong‐Magnetic Flexible Composites for Magnetically Responsive Soft Robots

open access: yesAdvanced Robotics Research, EarlyView.
This perspective provides an overview of the performance mechanisms, preparation methods, and applications of strong magnetic flexible composite materials in soft actuators (such as gripping, movement, and sensing), and further explores current opportunities and challenges.
Wenwen Li   +4 more
wiley   +1 more source

Metabologenomic Hallmark‐Based Discovery of Bacterial Thioamides as a New Lead against Drug‐Resistant Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
A targeted metabologenomic strategy integrating genomic and metabolomic hallmarks enabled the discovery of two new thioamides, thiogochangamides A and B, from bacteria. Their absolute configurations, previously unresolved within the thioviridamide family, were fully assigned through various chemical derivatizations and computational analysis ...
Young Eun Du   +18 more
wiley   +1 more source

TGFβ1 Activates Lnc‐APUE to Promote Tumor Metastasis via the Alu Element‐Driven STAU1‐Mediated Decay of CDH1 mRNA

open access: yesAdvanced Science, EarlyView.
We delineate a TGFβ1/SMAD/lnc‐APUE/E‐cadherin axis wherein TGFβ1 signaling activates lnc‐APUE; lnc‐APUE subsequently downregulates E‐cadherin expression via Alu element‐driven STAU1‐mediated decay of CDH1 mRNA, thereby promoting tumor metastasis. Our findings reveal a novel regulatory function for lnc‐APUE within the SMD pathway, elucidate a distinct ...
Song‐Yang Li   +10 more
wiley   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

open access: yesAdvanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian   +7 more
wiley   +1 more source

The introduction of marine cone snail species from the coast of the Qeshm Island, contains conotoxin palliative pain in mice [PDF]

open access: yesبوم‌شناسی آبزیان, 2019
Conotoxins are small toxic peptides that are synthesized in cone snail venom ducts. Conotoxins have analgesic effects in models animal. In this study, the analgesic effects with no toxicity of Persian Gulf cone snails, Conus coronatus, and Conus frigidus
Halimeh Rajabi   +4 more
doaj  

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