Results 41 to 50 of about 118,470 (252)

Snail acetylation by autophagy‐derived acetyl‐coenzyme A promotes invasion and metastasis of KRAS‐LKB1 co‐mutated lung cancer cells

Cancer Communications, 2022
Background Autophagy is elevated in metastatic tumors and is often associated with active epithelial‐to‐mesenchymal transition (EMT). However, the extent to which EMT is dependent on autophagy is largely unknown.
Jang Hee Han, Yong Keon Kim, Hakhyun Kim, Jooyoung Lee, Myung Joon Oh, Sang Bum Kim, Minjee Kim, Kook Hwan Kim, Hyun Ju Yoon, Myung‐Shik Lee, John D. Minna, Michael A. White, Hyun Seok Kim   +12 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Effects of snails, submerged plants and their coexistence on eutrophication in aquatic ecosystems

Knowledge and Management of Aquatic Ecosystems, 2017
Eutrophication resulting from nutrient loading to freshwater habitats is a severe problem, leading to degradation of ecosystems, including deterioration of water quality, water clarity and loss of biodiversity.
Mo Shuqing, Zhang Xiufeng, Tang Yali, Liu Zhengwen, Kettridge Nicholas   +4 more
doaj   +1 more source

Report of rotifer-ciliate-gastropod hyperepibiosis found on snail (Mollusca) from Goa, India

Acta Biologica, 2021
Here we report a rotifer-ciliate-gastropod hyperepibiosis in freshwater canal, Goa, India. A rotifer Philodina cf. megalotrocha Ehrenberg, 1832 was found attached on the colony of Epistylis plicatilis Ehrenberg, 1838 which was epibiont on gastropod ...
Tapas Chatterjee, Igor Dovgal, Aniket Desai, Mandar Nanajkar   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Host Shaping Associated Microbiota in Hydrothermal Vent Snails from the Indian Ocean Ridge

Biology
Snails at hydrothermal vents rely on symbiotic bacteria for nutrition; however, the specifics of these associations in adapting to such extreme environments remain underexplored.
Xiang Zeng, Jianwei Chen, Guilin Liu, Yadong Zhou, Liping Wang, Yaolei Zhang, Shanshan Liu, Zongze Shao   +7 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

The Black Consciousness Movement in South Africa: A Product of The Entire Black World

Historia Actual On-Line, 2009
El trabajo ilustra cómo el surgimiento del Movimiento de Conciencia Negra en Sudáfrica puede estar diametralmente unido a la emergencia de los movimientos de Conciencia Negra y Black Power en América.
Mgwebi Snail
doaj  

Lipids analysis in hemolymph of African giant Achatina fulica (Bowdich, 1822) exposed to different photoperiods

Brazilian Journal of Biology
The influence of different photophases (0, 6, 12, 18 and 24 hours) on the triglycerides and total cholesterol contents in the hemolymph of A. fulica was evaluated, since there is no information in the literature about the influence of this factor on ...
D. Lustrino, VM. Tunholi-Alves, VM. Tunholi, MP. Marassi, J. Pinheiro   +4 more
doaj   +1 more source

Downregulation of CHIP promotes ovarian cancer metastasis by inducing Snail‐mediated epithelial–mesenchymal transition

Molecular Oncology, 2019
The epithelial–mesenchymal transition (EMT) plays a pivotal role in the conversion of early‐stage tumors into invasive malignancies. The transcription factor Snail, an extremely unstable protein whose subcellular levels are regulated by many E3 ubiquitin
Sun‐Mi Park, Seung‐Ho Park, Ki‐Jun Ryu, In‐Kyu Kim, Hyeontak Han, Hyo‐Jin Kim, Seon‐Hee Kim, Keun‐Seok Hong, Hyemin Kim, Minju Kim, Bok Im Cho, Jeong Doo Heo, Na Hyun Kim, Eun Mi Hwang, Jae‐Yong Park, Jong In Yook, Hee Jun Cho, Cheol Hwangbo, Kwang Dong Kim, Hoseok Song, Jiyun Yoo   +20 more
doaj   +1 more source