Results 81 to 90 of about 77,523 (237)

Different Pattern of Treatment Failure After Chemoradiation Between p16+ and p16− Patients Affected by Oropharyngeal Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Oropharyngeal cancer (OPC) exhibits distinct clinical behaviors according to HPV/p16 status and smoking exposure. While HPV‐positive OPC generally shows superior survival, differences in recurrence patterns remain unclear. Methods A retrospective multicenter analysis of 674 AJCC VII edition Stage III–IVa/b OPC patients treated with ...
Riccardo Gili, Paolo Bossi, Luca Lalli, Lisa Francesca Linda Licitra, Marta Maddalo, Almalina Bacigalupo, Liliana Belgioia, Jon Cacicedo, Nadia Facchinetti, Almudena Garcia Castano, Marc Oliva, Pierluigi Bonomo, Giuseppe Sanguineti, Pierfrancesco Franco, Athanassios Argiris, Amanda Psyrri, Ester Orlandi   +16 more
wiley   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

Gut microbiome‐derived metabolites show promise in cancer research and therapy

Interdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang, Yifan Wang, Daolin Tang, Peilong Li, Lutao Du   +4 more
wiley   +1 more source

Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management

Journal of Applied Toxicology, EarlyView.
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz, Bayram Göktaş, İlker Ateş, Mustafa Çelik   +3 more
wiley   +1 more source

Microemulsion‐Based Drilling Fluids Incorporating Seashell Residue Powder: A Sustainable Approach to Fluid Loss Control

Journal of Surfactants and Detergents, EarlyView.
Two microemulsion‐based drilling fluids incorporating SSRP were formulated using pine oil, the nonionic surfactant Alkonat L100W, and a glycerol/water solution. The results provide valuable insights into how surfactant‐assisted microemulsion systems can be engineered to enhance the performance and eco‐efficiency of drilling fluids.
Luara Ribeiro Viana, Raphael Ribeiro da Silva, João Pedro Gonçalves de Souza Soares, José Cavalcante de Queiroz Neto, Maria Eduarda Araújo Pessoa, Rafael Peixoto Alves, Fabiola Dias da Silva Curbelo   +6 more
wiley   +1 more source

Gender and Land Degradation Neutrality (LDN): Evaluating Nigeria's Legislative Framework for Achieving Gender‐Equitable LDN Outcomes

Land Degradation &Development, EarlyView.
ABSTRACT Legislative frameworks that support gender equality are crucial for addressing structural inequalities, protecting women's rights, and achieving gender‐equitable land degradation neutrality (LDN) outcomes. This study examines the extent to which national‐level policies and legislation governing LDN and related sectors incorporate gender ...
Cynthia Nneka Olumba, Chukwudi Charles Olumba   +1 more
wiley   +1 more source

The Giant African Land Snail Achatina fulica (Bowdich, 1720) as a Candidate Species for Bioregenerative Life Support Systems [PDF]

Журнал Сибирского федерального университета: Серия Биология, 2015
The capability of snails to consume and convert inedible plant biomass and kitchen waste was tested. Inedible biomass of wheat and cabbage and also potato peels as a food were worse than lettuce, which is an ordinary feed for snails. In order to describe
Nicolay S. Manukovsky, Vladimir S. Kovalev, Alexander A. Tikhomirov, Galina S. Kalacheva, Anzhelika A. Kolmakova   +4 more
doaj  

Comparing non‐staining methods with Mutvei's solution to visualize growth increments in short‐lived intertidal marine gastropod shells

Limnology and Oceanography: Methods, EarlyView.
Abstract Mutvei's solution is a widely utilized standard staining method for revealing growth increments in biogenic carbonates; however, it is a slightly toxic, destructive approach with varying success across species groups. Therefore, there has been growing interest in finding non‐toxic, less destructive, and straightforward alternative techniques ...
Mahsa Alidoostsalimi, Amy L. Prendergast, Sean Ulm, Ariana B. J. Lambrides, Ian J. McNiven, Russell N. Drysdale, Nguurruumungu Indigenous Corporation, Walmbaar Aboriginal Corporation RNTBC   +7 more
wiley   +1 more source

Taking Pride in Vegan Consumption: A Construal Level Theory Account of Ad Message Appeal and Future Self Connectedness

Psychology &Marketing, EarlyView.
ABSTRACT Despite growing interest in vegan products, research examining the motivations, underlying psychological processes, and boundary conditions that drive consumer preference for vegan products remains limited. Drawing on theories of temporal self and appraisal theory, we find that an immediate message appeal (e.g., animal welfare), as compared to
Mona Safizadeh, Atefeh Yazdanparast, Reto Felix   +2 more
wiley   +1 more source

Bio‐Based Microfluidics With Snail Slime: A By‐Product of Agriculture Plays an Exciting Role in the Chemistry of Microfluidic Reaction Chambers

Macromolecular Rapid Communications, EarlyView.
Due to a broad spectrum of active ingredients, snail slime presents a variety of exciting physical properties and chemical reactivities. Especially in the role of the reduction‐ and stabilizing agent for the manufacturing of gold nanoparticles, its great potential is revealed. Utilising the proteins found in slime, Nanoparticle‐comprising hydrogels are
Andrea Koball, Jens Gaitzsch
wiley   +1 more source