Results 71 to 80 of about 106,824 (308)

Cytometric analysis, genetic manipulation and antibiotic selection of the snail embryonic cell line Bge from Biomphalaria glabrata, the intermediate host of Schistosoma mansoni. [PDF]

, 2015
The invertebrate cell line, Bge, from embryos of the snail Biomphalaria glabrata, remains to date the only established cell line from any species of the Phylum Mollusca.
Knight, M, Nacif-Pimenta, Rafael, Nacif-Pimenta, R, Yan, H, Yan, Hongbin, Mann, V, Mann, Victoria H., Brindley, P, Bridger, J, Brindley, Paul J., Pimenta, Rafael Nacif, Bridger, Joanna, Matchimakul, P, Matchimakul, Pitchaya, Knight, Matty, Smout, M, Smout, Michael J., Rinaldi, G, Rinaldi, Gabriel   +18 more
core   +1 more source

DTX3L Inhibits the EMT, Metastasis, and Stem‐Like Features of Gastric Cancer Through Promoting GSK‐3β Dependent SNAI1 Decay

Advanced Science, EarlyView.
This research identifies DTX3L as a critical tumor suppressor that inhibits epithelial‐mesenchymal transition (EMT), invasion and metastasis in gastric cancer. By functioning as an E3 ubiquitin ligase, DTX3L targets the master EMT regulator SNAI1 for GSK‐3β‐dependent proteasomal degradation.
Yang Chen, Zhen Li, Jiajia Shen, Jingyu Lin, Xiaoli Zhao, Rui Zhang, Ying Han, Zhen Wang   +7 more
wiley   +1 more source

Evidence for survival of Pleistocene climatic changes in Northern refugia by the land snail Trochoidea geyeri (Soós 1926) (Helicellinae, Stylommatophora)

, 2003
The study of organisms with restricted dispersal abilities and presence in the fossil record is particularly adequate to understand the impact of climate changes on the distribution and genetic structure of species.
Pfenninger Markus, Markus Pfenninger, Pfenninger, Markus, David Posada, Magnin, Frédéric, Magnin Frédéric, Posada, David, Frédéric Magnin, Posada David   +8 more
core   +1 more source

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source

The introduction of marine cone snail species from the coast of the Qeshm Island, contains conotoxin palliative pain in mice [PDF]

بوم‌شناسی آبزیان, 2019
Conotoxins are small toxic peptides that are synthesized in cone snail venom ducts. Conotoxins have analgesic effects in models animal. In this study, the analgesic effects with no toxicity of Persian Gulf cone snails, Conus coronatus, and Conus frigidus
Halimeh Rajabi, Hossein Zolgharnen, Mohammad Taghi Ronagh, Ahmad Savari, Mohammad Sharif Ranjbar   +4 more
doaj  

A species delimitation approach in the Trochulus sericeus/hispidus complex reveals two cryptic species with a sharp contact zone [PDF]

, 2009
Background: Mitochondrial DNA sequencing increasingly results in the recognition of genetically divergent, but morphologically cryptic lineages. Species delimitation approaches that rely on multiple lines of evidence in areas of co-occurrence are ...
Dépraz, Aline, Pfenninger Markus, Hausser, Jacques, Markus Pfenninger, Pfenninger, Markus, Pfenninger, M., Hausser, J., Aline Dépraz, Dépraz, A., Dépraz Aline, Hausser Jacques, Jacques Hausser   +11 more
core   +1 more source

Aptamer‐Targeted PrPC Drives Colorectal Cancer Metastasis via a LYN‐STAT3 Complex and Enables Liquid Biopsy Detection

Advanced Science, EarlyView.
The aptamer WHY‐3E identifies PrPC as a CRC driver. Stabilized by USP18, endocytosed PrPC forms a LYN/STAT3 complex, upregulating MSN transcription to promote metastasis. Crucially, WHY‐3E sensitively detects PrPC‐positive circulating exosomes, establishing a robust theoretical foundation for non‐invasive clinical diagnostics.
Chunlin Wang, Hongyu Wu, Chaojing Zheng, Hao Zhang, Xiaoqiu Wu, Jiaqi Wang, Zewen Chang, Jun Xiang, Yunxiao Liu, Chenkai Zhang, Yuliuming Wang, Hao Jiang, Yuchen Zhong, Jun Luo, Ying Chen, NaNa Zhang, Weiyuan Zhang, Ziming Yuan, ChaoXia Zou, Weihong Tan, Meng Wang, Hanqing Hu, Tao Bing, Guiyu Wang   +23 more
wiley   +1 more source

Machine Learning‐Driven Prediction of Microplastic Aging Processes and Environmental Risk Assessment Across Multi‐Media Systems

Advanced Science, EarlyView.
This perspective proposes a cohesive machine learning strategy to decode microplastic aging. It advocates for Federated Learning to dismantle global data silos and introduces the TRACE framework (TRansport, Aging, Corona, Ecotoxicity). By integrating physics‐informed modeling with causal discovery, this approach bridges the laboratory‐field gap to ...
Yaping Lyu, Xinran Qiu, Xing Li, Tianhuan Yang, Xuetao Guo, Hao Qiu, Peng Zhang   +6 more
wiley   +1 more source

Valuing the Prevention of an Infestation: The Threat of the New Zealand Mud Snail in Northern Nevada [PDF]

The Truckee / Carson / Walker River Watershed in Northern Nevada is under an imminent threat of infestation by the New Zealand Mud Snail, an aquatic nuisance species with the potential to harm recreational fisheries. We combine a utility-theoretic system-
Klaus Moeltner, Allison Davis
core  

Epidemiology of Angiostrongylus cantonensis and eosinophilic meningitis in the People's Republic of China [PDF]

, 2011
Background: Human eosinophilic meningitis is mainly caused by the rat lungworm Angiostrongylus cantonensis, especially in tropical and subtropical regions.
Lv, Shan
core   +1 more source