Results 81 to 90 of about 79,869 (259)

Knockdown of long non‐coding RNA linc‐ITGB1 inhibits cancer stemness and epithelial‐mesenchymal transition by reducing the expression of Snail in non‐small cell lung cancer

Thoracic Cancer, 2019
Background The main cause of death in patients with non‐small cell lung cancer (NSCLC) is the progression of cancer metastasis, which can be attributed to multiple factors, such as cancer stem cells (CSCs) and epithelial‐mesenchymal transition (EMT ...
Lili Guo, Cencen Sun, Shilei Xu, Yue Xu, Qiuping Dong, Linlin Zhang, Wei Li, Xingyu Wang, Guoguang Ying, Fengjie Guo   +9 more
doaj   +1 more source

Structural and Functional Stability of Natural Actomyosin From Freshwater Snail (Bellamya bengalensis): Unraveling Thermal and pH Effects

Food Chemistry International, EarlyView.
Natural actomyosin from B. bengalensis exhibited maximum solubility (∼69.9%) at 40°C and stability near neutral pH, with minimum solubility at pH 4. Surface hydrophobicity and emulsifying activity peaked at 50°C, whereas Ca2+‐ATPase and foaming peaked at 40°C. DSC and SDS–PAGE confirmed denaturation above 40°C.
Krishan Kumar Yadav, Naresh Kumar Mehta, Sanjeev Sharma, M. Bhargavi Priyadarshini, Himanshu Priyadarshi, Prasenjit Pal, Harjeet Nath, Sneha Chaudhury   +7 more
wiley   +1 more source

Heart rate and body weight alterations in juvenile specimens of the tropical land snail Megalobulimus sanctipauli during dormancy

Brazilian Journal of Medical and Biological Research, 2001
The time course of heart rate and body weight alterations during the natural period of dormancy were determined in active feeding and dormant juvenile specimens of Megalobulimus sanctipauli.
Rizzatti A.C.S., Romero S.M.B.
doaj  

Food Contamination and Safety in Nigeria: A Systematic Synthesis of Heavy Metals, Microbial Pathogens, and Health Risk Metrics

Food Safety and Health, EarlyView.
This is an infographic driver of food contaminants and health effects. ABSTRACT Food safety remains a critical challenge in Nigeria due to rapid urbanization and weak regulatory enforcement. This systematic review synthesizes empirical evidence from 2015 to 2025 to characterize food contaminant profiles and associated human health risks in Nigeria ...
Cecilia Nwadiuto Obasi, Naomi A. Mogborukor, Baridoo Donatus Dooka, Polycarp Dauda Madaki, Chiara Frazzoli, Mohamed Haddad, Orish Ebere Orisakwe   +6 more
wiley   +1 more source

Nanoplastics: Methods, Exposure and Effects on Domestic, Farm and Wild Animals

Journal of Applied Toxicology, EarlyView.
ABSTRACT Nanoplastics (NPs) are synthetic polymer particles ranging in size from 1 nm to 1 μm that have been identified as a major concern for ecosystems and organisms due to their plethora of negative effects. The aim of this review is to provide a comprehensive overview of the knowledge relating to exposure and effects of NPs in domestic (i.e., farm ...
B. De Felice, M. Bertazzo, A. F. Tabaran, M. Parolini, R. P. Popa, A. Pintea, L. J. Spicer, A‐L. Nagy, F. Caloni   +8 more
wiley   +1 more source

Ostracod faunal and geochemical evidence for the impact of Hoxnian (MIS 11c) sea levels in eastern England

Journal of Quaternary Science, EarlyView.
ABSTRACT Marine isotope substage 11c (~426–366 ka) is widely regarded as the most recent Pleistocene interglacial that is broadly analogous to the Holocene. The timing and magnitude of sea‐level changes during MIS 11 have been much debated, particularly concerning whether sea levels were significantly higher than during the Holocene. Empirical evidence
Tom S. White, Jonathan A. Holmes, David J. Horne, David R. Bridgland   +3 more
wiley   +1 more source

Breast Cancer‐Derived AZU1 Educates Neutrophils to Promote Tumor Progression and Metastasis Through PAD4‐Dependent Extracellular Trap Formation

Molecular Carcinogenesis, EarlyView.
ABSTRACT Neutrophil extracellular traps (NETs) play crucial roles in cancer progression, but their regulatory mechanisms in breast cancer remain poorly understood. We developed a NETs‐related prognostic risk model using TCGA breast cancer data and identified key biomarkers through bioinformatics analysis.
Zhen Huang, Zhe Wu, Guiyue Zhu, Fangyu Qiu, Lihui Li, Yujie Xie, Chunyu Wei, Yinhua Pan, Quanqing Zou, Yuntian Tang   +9 more
wiley   +1 more source

Chemopreventive Effect of Bitter Melon (Momordica charantia) Juice on Pancreatic Carcinogenesis in LSL‐KrasG12D/+; p48Cre/+ Mice

Molecular Carcinogenesis, EarlyView.
ABSTRACT Herein, using the LSL‐KrasG12D/+; p48Cre/+ transgenic mouse model [that recapitulates the full spectrum of human disease, progressing from early pancreatic intraepithelial neoplasia lesions to invasive pancreatic ductal adenocarcinoma (PDAC)], we determined the chemopreventive effect of long‐term (chronic) administration of Bitter Melon Juice (
Lakshmi Sai Pratyusha Bugata, Deepanshi Dhar, Rama Kant, Robin Kumar, Md. Imtiazul Kabir, Chapla Agarwal, Rajesh Agarwal, Komal Raina   +7 more
wiley   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Interplanetary frontiers: terraforming from an invasion science perspective

Oikos, EarlyView.
The pursuit of a multi‐planetary existence represents one of humanity's greatest frontiers. If applied justly, it offers an opportunity to extend its civilization's lifespan amid escalating sustainability crises on Earth. One approach increasingly gaining traction is terraforming, a hitherto theoretical ecological and evolutionary experiment revolving ...
Teun Everts, Ronaldo Sousa, Phillip J. Haubrock   +2 more
wiley   +1 more source