Results 101 to 110 of about 191,305 (374)
Advanced Science, EarlyView.We delineate a TGFβ1/SMAD/lnc‐APUE/E‐cadherin axis wherein TGFβ1 signaling activates lnc‐APUE; lnc‐APUE subsequently downregulates E‐cadherin expression via Alu element‐driven STAU1‐mediated decay of CDH1 mRNA, thereby promoting tumor metastasis. Our findings reveal a novel regulatory function for lnc‐APUE within the SMD pathway, elucidate a distinct ...
Song‐Yang Li +10 more
wiley +1 more source
Memorias do Instituto Oswaldo Cruz, 2011 A real-time polymerase chain reaction (PCR) assay with fluorescence resonance energy transfer (FRET) hybridisation probes combined with melting curve analysis was developed to detect Schistosoma japonicum in experimentally infected snails and in faecal ...
Tongjit Thanchomnang +6 more
doaj +1 more source
CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target
Advanced Science, EarlyView.This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang +2 more
wiley +1 more source
A Survey of Medically Important Snails of Gahar Lake in Lorestan Province, Iran
Journal of Medical Microbiology and Infectious Diseases, 2014 Introduction: Some snails play an important role in the transmission of helminthes, mainly trematodes of medical and veterinary importance. There seems to be no information on the freshwater snails of Gahar Lake in Lorestan province of Iran.
Rouhollah Valipour Nouroozi
doaj
Memorias do Instituto Oswaldo Cruz, 2004 The first and second internal transcribed spacer regions (ITS1 and ITS2) of the ribosomal DNA of Biomphalaria tenagophila complex (B. tenagophila, B. occidentalis, and B. t. guaibensis) were sequenced and compared.
Teofânia HDA Vidigal +6 more
doaj +1 more source
Status of Three Species of Freshwater Snails (Gastropoda: Pleuroceridae) in the Lower Ohio River Basin, Illinois [PDF]
, 2009 Illinois Department of Natural Resources Wildlife Preservation Fund Grant/Contract No: RC08-L20WWe report on a status survey of Lithasiaspp. (Gastropoda:Pleuroceridae) we conducted in the Ohio River basin, Illinois.
Cummings, Kevin S., Tiemann, Jeremy S.
core
Notes on the Food of Cychrini (Coleoptera: Carabidae) [PDF]
, 2017 In this paper, the food of nineteen species of Cychrini is given, for three genera: Cychrus, Scaphinotus and Sphaeroderus. The beetles of this tribe seem to be nearly exclusively carnivorous, feeding principally on snails and slugs, exceptionally on ...
Larochelle, Andre
core +3 more sources
Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Advanced Science, EarlyView.Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
Differentiation of Schistosoma haematobium from related schistosomes by PCR amplifying an inter-repeat sequence. [PDF]
, 2007 Schistosoma haematobium infects nearly 150 million people, primarily in Africa, and is transmitted by select species of local bulinid snails. These snails can host other related trematode species as well, so that effective detection and monitoring of ...
Abbasi, Ibrahim +5 more
core +1 more source
Advanced Science, EarlyView.Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin +12 more
wiley +1 more source