Results 41 to 50 of about 191,305 (374)

Insights from an Integrated View of the Biology of Apple Snails (Caenogastropoda: Ampullariidae)

, 2015
Apple snails (Ampullariidae) are among the largest and most ecologically important freshwater snails. The introduction of multiple species has reinvigorated the field and spurred a burgeoning body of research since the early 1990s, particularly regarding
K. Hayes, K. Hayes, K. Hayes, R. Burks, Alfredo Castro-Vasquez, P. C. Darby, H. Heras, P. Martín, J. Qiu, S. Thiengo, I. Vega, I. Vega, T. Wada, Y. Yusa, S. Burela, M. Cadierno, J. A. Cueto, Federico A. Dellagnola, M. Dreon, M. V. Frassa, Maximiliano Giraud-Billoud, M. S. Godoy, S. Ituarte, E. Koch, K. Matsukura, M. Y. Pasquevich, C. Rodriguez, L. Saveanu, M. E. Seuffert, E. Strong, Jin Sun, N. Tamburi, María J. Tiecher, R. Turner, Patricia L. Valentine-Darby, R. Cowie, Argentina. Comisión de Investigaciones Científicas . La Plata   +36 more
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Venomous secretions from marine snails of the Terebridae family target acetylcholine receptors [PDF]

, 2013
Venoms from cone snails (Conidae) have been extensively studied during the last decades, but those from other members of the suborder Toxoglossa, such as of Terebridae and Turridae superfamilies attracted less interest so far. Here, we report the effects
Kauferstein, Silke, Kendel, Yvonne, Kurz, Alexander, Mebs, Dietrich, Melaun, Christian, Nicke, Annette, Peigneur, Steve, Tytgat, Jan, Wunder, Cora   +8 more
core   +3 more sources

Glabralysins, potential New β-pore-forming toxin family members from the schistosomiasis vector snail biomphalaria glabrata [PDF]

, 2020
Biomphalaria glabrata is a freshwater Planorbidae snail. In its environment, this mollusk faces numerous microorganisms or pathogens, and has developed sophisticated innate immune mechanisms to survive.
Crickmore, Neil, Duval, David, Galinier, Richard, Gourbal, Benjamin, Lassalle, Damien, Pinaud, Silvain, Tetreau, Guillaume   +6 more
core   +3 more sources

Susceptibility of Snails to Infection with Schistosomes is influenced by Temperature and Expression of Heat Shock Proteins

Epidemiology, 2015
The freshwater snail, Biomphalaria glabrata is the obligate intermediate host for the transmission of the parasitic trematode, Schistosoma mansoni the causative agent of the chronic debilitating neglected tropical disease, schistosomiasis.
M. Knight, O. Elhelu, M. Smith, B. Haugen, André N. Miller, N. Raghavan, Christopher Wellman, C. Cousin, F. Dixon, V. Mann, G. Rinaldi, W. Ittiprasert, P. Brindley   +12 more
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Měkkýši přírodních památek V Krátkých a Lom Rasová v CHKO Bílé Karpaty [PDF]

Malacologica Bohemoslovaca
The V Krátkých Nature Monument (NM) comprises of landscape mosaic of meadows, groves, spring fen and wetland while the Lom Rasová NM is a former sandstone quarry with open and forested areas.
Radovan Coufal
doaj   +1 more source

Modulation of defensive reflex conditioning in snails by serotonin

Frontiers in Behavioral Neuroscience, 2015
Highlights Daily injection of serotonin before a training session accelerated defensive reflex conditioning in snails. Daily injection of 5-hydroxytryptophan before a training session in snails with a deficiency of serotonin induced by the “neurotoxic ...
V. V. Andrianov, T. Bogodvid, I. Deryabina, A. Golovchenko, L. Muranova, Roza R. Tagirova, A. Vinarskaya, Kh. L. Gainutdinov   +7 more
semanticscholar   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Morphological and polymerase chain reaction-restriction fragment lenght polymorphism characterization of Biomphalaria kuhniana and Biomphalaria amazonica from Colombia

Memorias do Instituto Oswaldo Cruz, 2002
In Colombia, five Biomphalaria planorbid species are known: B. kuhniana, B. straminea, B. peregrina, B. canonica and B. oligoza(var. B. philippiana). Among them, B. straminea is intermediate host of Schistosoma mansoni and B.
Luz E Velásquez, Roberta L Caldeira, Victoria Estrada, Omar S Carvalho   +3 more
doaj   +1 more source