Results 101 to 110 of about 75,123 (237)

A synthetic biology approach for consistent production of plant-made recombinant polyclonal antibodies against snake venom toxins [PDF]

, 2018
Antivenoms developed from the plasma of hyperimmunized animals are the only effective treatment available against snakebite envenomation but shortage of supply contributes to the high morbidity and mortality toll of this tropical disease.
Arnold, Beerli, Bendandi, Bolanos, Chippaux, Elena, Frauches, Gene, Graham, Gutierrez, Gutierrez, Gutierrez, Gutierrez, Gutierrez, Gutierrez, Gutierrez, Harrison, Julve, Laustsen, Laustsen, Lavonas, Marillonnet, Marillonnet, Paul, Paul, Pla, Qiu, Ramos, Rasmussen, Sarrion-Perdigones, Segura, Soller, Stock, Stoger, Syller, Theakston, Walwyn, Wang, Zheng   +38 more
core   +2 more sources

Protein design and RNA design: Perspectives

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract Advances in deep learning and generative modeling have transformed the landscape of protein and RNA design, enabling rapid and precise creation of novel biomolecules with tailored structures and functions. In protein design, generative deep learning frameworks now support backbone generation, sequence optimization, and joint sequence–structure
Xi Chen, Xu Dai, Peilong Lu
wiley   +1 more source

The wide gape of snakes: A comparison of the developing mandibular symphysis in sauropsids

Journal of Anatomy, Volume 248, Issue 6, Page 937-949, June 2026.
Our analysis explores the adaptations at the mandibular symphysis required to allow extreme lower jaw mobility in macrostomate snakes taking a comparative approach. Abstract The origin and evolution of snakes has been marked by the acquisition of many morphological and functional novelties, one of which is the possession of a highly kinetic skull ...
Maricci Basa, Neal Anthwal, Ryan N. Felice, Abigail S. Tucker   +3 more
wiley   +1 more source

Computational Studies of Snake Venom Toxins

Toxins, 2017
Most snake venom toxins are proteins, and participate to envenomation through a diverse array of bioactivities, such as bleeding, inflammation, and pain, cytotoxic, cardiotoxic or neurotoxic effects.
Paola G. Ojeda, David Ramírez, Jans Alzate-Morales, Julio Caballero, Quentin Kaas, Wendy González   +5 more
doaj   +1 more source

CNC–PNIPAM Drug Delivery System Improves Endometrial Receptivity via Natural Killer Cell Immune Tolerance in Endometriosis

Advanced NanoBiomed Research, Volume 6, Issue 5, May 2026.
An injectable CNC–PNIPAM hydrogel is developed for intrauterine co‐delivery of levonorgestrel and botropase. This platform reprograms uterine natural killer cells toward an immune–tolerant phenotype and enhances endometrial receptivity marker expression. The results demonstrate a promising strategy to counteract endometriosis–associated infertility and
Zhou Liang, Yingjie Wang, Chenyu Bai, Pengfei Li, Xin He, Meng Ma, Xiaoying Luo, Yi Song, Yao Li, Yun Wang   +9 more
wiley   +1 more source

Distinct regulatory networks control toxin gene expression in elapid and viperid snakes

BMC Genomics
Background Venom systems are ideal models to study genetic regulatory mechanisms that underpin evolutionary novelty. Snake venom glands are thought to share a common origin, but there are major distinctions between venom toxins from the medically ...
Cassandra M. Modahl, Summer Xia Han, Jory van Thiel, Candida Vaz, Nathan L. Dunstan, Seth Frietze, Timothy N. W. Jackson, Stephen P. Mackessy, R. Manjunatha Kini   +8 more
doaj   +1 more source

The use of snake venom toxins in medicine [PDF]

, 2010
Zmije se unutar skupine gmazova počinju odvajati u Kredi (geološko razdoblje Mezozoika koje je trajalo od prije 136 do pred 65 milijuna godina). Mogućnost stvaranja otrova razvijaju tokom Miocena (geološko razdoblje Neogena koje je trajalo od prije 23.03
Mavrović, Martina
core   +2 more sources

Hypotheses for the Adaptive Maintenance of Phenotypic Polymorphisms

Ecology and Evolution, Volume 16, Issue 5, May 2026.
Phenotypic polymorphisms offer easily observable diversity ideal for empirical and theoretical exploration, but developing and comparing hypotheses for the adaptive maintenance of polymorphism can be a challenge. Here, we propose a framework categorizing polymorphisms based on (i) one of five distinct types of maintenance selection and (ii) the context
Jay J. Falk, Michael S. Webster, Dustin R. Rubenstein   +2 more
wiley   +1 more source

Population‐Level Laterality of Ambush Posture in the Chinese Green Tree Pit Viper (Trimeresurus stejnegeri) in Northern Taiwan

Ecology and Evolution, Volume 16, Issue 5, May 2026.
In the Chinese green tree pit viper (Trimeresurus stejnegeri), we tested whether ambush posture shows population‐level laterality using 283 photographic records from nocturnal field surveys and verified iNaturalist observations across three regions in northern Taiwan.
Hung‐Chia Chang, Si‐Min Lin
wiley   +1 more source

Analysis of the venom components of necrotic tissue exudates from Naja atra venom-infected Guangxi Bama miniature pigs

Guangxi Yike Daxue xuebao
Objective To investigate the components of snake venom and the dynamic changes in protein expression in the exudates of necrotic tissues affected by the Naja atra venom in Guangxi Bama miniature pigs.
XIAO Manqi, GUAN Zhezhe, HU Shaocong, LI Yalan, ZHANG Ziyan, JIANG Ningjing, ZHANG Xuerong, LIAO Ming   +7 more
doaj   +1 more source