Results 101 to 110 of about 134,784 (231)

Open‐land‐derived agroforestry and effects of abandonment of management of the main crop on ecosystem services and woody plant diversity

PLANTS, PEOPLE, PLANET, Volume 8, Issue 5, Page 1805-1816, September 2026.
Tropical forests are rapidly declining. One promising strategy to reverse the loss of tropical forest is the establishment of agroforestry on open land. We combined interviews with biodiversity surveys to learn general lessons from success and nonsuccess stories of the establishment of open‐land‐derived coffee agroforests in one of the world's ...
Lucas M. Fonzaghi, Kristoffer Hylander, Thiago S. de Melo, Ayco J. M. Tack   +3 more
wiley   +1 more source

Analysis of the venom components of necrotic tissue exudates from Naja atra venom-infected Guangxi Bama miniature pigs

Guangxi Yike Daxue xuebao
Objective To investigate the components of snake venom and the dynamic changes in protein expression in the exudates of necrotic tissues affected by the Naja atra venom in Guangxi Bama miniature pigs.
XIAO Manqi, GUAN Zhezhe, HU Shaocong, LI Yalan, ZHANG Ziyan, JIANG Ningjing, ZHANG Xuerong, LIAO Ming   +7 more
doaj   +1 more source

Elapid Snake Venom Analyses Show the Specificity of the Peptide Composition at the Level of Genera Naja and Notechis

Toxins, 2014
Elapid snake venom is a highly valuable, but till now mainly unexplored, source of pharmacologically important peptides. We analyzed the peptide fractions with molecular masses up to 10 kDa of two elapid snake venoms—that of the African cobra, N.
Aisha Munawar, Maria Trusch, Dessislava Georgieva, Diana Hildebrand, Marcel Kwiatkowski, Henning Behnken, Sönke Harder, Raghuvir Arni, Patrick Spencer, Hartmut Schlüter, Christian Betzel   +10 more
doaj   +1 more source

Medically important differences in snake venom composition are dictated by distinct postgenomic mechanisms [PDF]

, 2014
Variation in venom composition is a ubiquitous phenomenon in snakes and occurs both interspecifically and intraspecifically. Venom variation can have severe outcomes for snakebite victims by rendering the specific antibodies found in antivenoms ...
Plan, D., Casewell, Nicholas R., Cook, Darren A. N., Pla, Davinia, Calvete, Juan J, Bolton, F.M.S., Wagstaff, Simon C, Bolton, Fiona M S, Calvete, J.J., King, Sarah I., King, Sarah I, Wüster, Wolfgang, Harrison, Robert A, Bolton, Fiona M.S., Harrison, R.A., King, S.I., Wagstaff, S.C., Cook, Darren A N, Casewell, Nick; id_orcid, Wagstaff, Simon C., Harrison, Robert A., Bolton, Fiona M. S., Sanz. L.,, Cook, Darren A.N., Harrison, Robert, Sanz, Libia, Casewell, N.R., Cook, D.A.N., Casewell, Nicholas R, Calvete, Juan J., Wüster, W., Wagstaff, Simon   +31 more
core   +1 more source

Systemic impact of intramuscular snake envenomation and intravenous immunoglobulin‐based antivenom treatment on murine plasma proteome and peptidome

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Snake envenomation remains a critical global public health challenge. In Brazil, the genus Bothrops is responsible for most accidents, typically resulting in coagulopathy, hemorrhage, and renal failure. Despite its clinical prevalence, the molecular mechanisms driving plasma protein disturbances remain poorly understood.
Bianca C. S. C. de Barros, Alison F. A. Chaves, Mariana S. L. C. Morone, Ana T. A. Sachetto, Marcelo L. Santoro, Oliver Schilling, Solange M. T. Serrano   +6 more
wiley   +1 more source

Chemically Regulated STING‐Activating Prodrugs of Deoxyribose Cyclic Dinucleotides Elicit Robust Immune Activation and Durable Antitumor Immunity

Angewandte Chemie, Volume 138, Issue 35, 24 August 2026.
All three diastereoisomers of an esterase‐sensitive phosphotriester dCDN prodrug demonstrate improved activity. The (Rp,Rp) diastereoisomer shows the highest activity with an EC50 of 1.7 nM in STING activation and displays the most pronounced antitumor activity via intravenous administration, significantly suppressing tumor proliferation, extending the
Zhiqiang Xie, Huimin Liu, Yuchen Yang, Xiaohan Sun, Jingwen Wang, Tianxiang Liu, Baifan Wang, Wenrui Qiu, Yiwen Sun, Yuting Bai, Yao Zhang, Dejun Ma, Rong Xiang, Shibo Li, Zhen Xi   +14 more
wiley   +2 more sources

Neotropical Rattlesnake (Crotalus simus) Venom Pharmacokinetics in Lymph and Blood Using an Ovine Model

, 2020
The most abundant protein families in viper venoms are Snake Venom Metalloproteases (SVMPs), Snake Venom Serine Proteases (SVSPs) and Phospholipases (PLA(2)s).
Lourival D. Possani, Neri-Castro, Edgar, Possani, Lourival D., Dayanira Paniagua, Alejandro Alagón, Fernando Zamudio, Melisa Bénard-Valle, Camilo Romero, Lopez-Casillas, Fernando, Olvera, Alejandro, Alagon, Alejandro, Alejandro Olvera, Edgar Neri-Castro, Romero, Camilo, Fernando López-Casillas, Boyer, Leslie, V, Paniagua, Dayanira, Zamudio, Fernando, Leslie V. Boyer, Benard-Valle, Melisa   +19 more
core   +1 more source

Total synthesis and structural characterization of a novel protein scaffold from the snail Biomphalaria glabrata

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Disulfide‐rich miniproteins constitute compact and highly stable scaffolds of growing interest for molecular and structural engineering. Schistosomins are ~80‐residue proteins conserved across gastropods that form a long‐standing orphan family whose structure and biological roles have remained unknown.
Oleg Melnyk, Stéphanie Caby, Armelle Vigouroux, Christine Demanche, Rémi Desmet, Magalie Sénéchal, Benoît Snella, Alexandra Mougel, Céline Boidin‐Wichlacz, Aurélie Parmentier, Ugo Pasco, Sonia Cantel, Solange Moréra, Jérôme Vicogne   +13 more
wiley   +1 more source

The effect of two novel C-type lectins, Ba100 and Ba25, isolated from the venom of the puff adder, Bitis arietans on T lymphocyte proliferative responses [PDF]

, 2008
Includes abstract. Includes bibliographical references (p. 233-318)
Spearman, Catherine Wendy Nest
core   +1 more source

Quantifying venom in African snakes: Insights into protein content, yield and body size associations

Toxicon: X
Snake venoms are complex mixtures primarily composed of toxic proteins used during prey capture and defence. There is limited knowledge concerning the protein concentration of snake venom and the biases of different protein determination methods.
Stephanie French, Rachael Da Silva, Martijn ten Have, Edouard Crittenden, Paul Rowley, India C. Cullen, Zachary Holland, Mark C. Wilkinson, Cassandra M. Modahl   +8 more
doaj   +1 more source