Results 51 to 60 of about 10,578 (200)

Engineering Antivenom: Research Progress and Future Directions in Snakebite Envenoming Therapy

Annals of the New York Academy of Sciences, Volume 1562, Issue 1, August 2026.
Snakebite envenoming therapy is evolving from plasma‐derived antivenoms toward rationally engineered therapeutics. Advances in toxicovenomics, structural biology, antibody engineering, computational protein design, recombinant expression, small‐molecule inhibitors, and diagnostics are enabling toxin‐centric development of safer, more effective, and ...
Andreas H. Laustsen
wiley   +1 more source

Severe Pediatric Snakebite With Coagulopathy and Compartment Syndrome: Conservative Management With Plasma Exchange

Clinical Case Reports, Volume 14, Issue 7, July 2026.
Therapeutic plasma exchange was successfully used in a child with severe snakebite envenomation complicated by refractory venom‐induced consumptive coagulopathy and suspected compartment syndrome, leading to full recovery and avoidance of surgical intervention.
Zain Mohammed Al Muqbel, Abdulrahman Al‐Majmuei, Ali Haider Ali, Naseem Yusuf Fahad, Reema Ajjawi, Amal Al Dailami, Afshan Lone, Manal Al Maskati, Nasser Mohamed Mansoor   +8 more
wiley   +1 more source

A Case Report of a Lebanon Viper ( Montivipera bornmuelleri) Envenomation in a Child

Clinical Practice and Cases in Emergency Medicine, 2022
Introduction: Snake envenomation is a serious public health concern. In the Middle East little is known about snakebite envenomation, which raises several challenges for emergency physicians caring for these patients. Case report: We report the case of a
Faysal Tabbara, Sarah S Abdul Nabi, Riad Sadek, Ziad Kazzi, Tharwat El Zahran   +4 more
doaj   +1 more source

A Case of Naja atra Bite Complicated by Gas Gangrene Leading to Amputation: Pathogen and Management Lessons

Clinical Case Reports, Volume 14, Issue 7, July 2026.
Gas gangrene of the right upper limb following a Naja atra bite, with extensive skin necrosis and purulent discharge. ABSTRACT Gas gangrene after a Naja atra bite may be caused by Enterococcus faecalis from the snake's mouth, which is resistant to ceftriaxone.
Xuan Ci, Wei‐Wen Guo, Lei Yang, Yue Zhang, Zi‐Jing Liang, Jun‐Ting Huang   +5 more
wiley   +1 more source

Snake Envenomation Causing Distant Tracheal Myonecrosis

Case Reports in Pulmonology, 2013
Snakebites are often believed to be poisonous. However, this is not always the case. In fact, each bite differs from snake to snake, depending on if the snake is poisonous and if there is envenomation.
Amina Khimani, Afton Mcnierney, Sara Surani, Salim Surani   +3 more
doaj   +1 more source

Viperid Envenomation Wound Exudate Contributes to Increased Vascular Permeability via a DAMPs/TLR-4 Mediated Pathway

Toxins, 2016
Viperid snakebite envenomation is characterized by inflammatory events including increase in vascular permeability. A copious exudate is generated in tissue injected with venom, whose proteomics analysis has provided insights into the mechanisms of venom-
Alexandra Rucavado, Carolina A. Nicolau, Teresa Escalante, Junho Kim, Cristina Herrera, José María Gutiérrez, Jay W. Fox   +6 more
doaj   +1 more source

Hospital admissions due to snake envenomation in the Republic of Cyprus: a 7-year retrospective review

Journal of Occupational Medicine and Toxicology, 2022
Background Snake envenomation is a major neglected tropical disease, lacking data in many countries including Cyprus, a Mediterranean island inhabited by the medically important blunt-nosed viper (Macrovipera lebetina). Reviewing the 2013–2019 period, we
Daniel Jestrzemski, Maria Athanasiadou, Vasos Scoutellas, Parviz Ghezellou, Bernhard Spengler, Frank Gessler, Ulrich Kuch   +6 more
doaj   +1 more source

Challenges of managing viper envenomation

APIK Journal of Internal Medicine, 2022
The signs and symptoms following snakebite envenomation vary according to the type of snake encountered. Typically, Viperidae (vipers) envenomates with a hemotoxin causing coagulopathy and muscle breakdown, while elapids envenomate with a neurotoxin ...
Purvesh Agrawal, Nidhi Khandelwal
doaj   +1 more source

Bioinformatics‐Driven Design and Evaluation of Recombinant Multi‐Epitope Immunogens Derived From Snake Venom Toxins as Potential Antivenom Candidates

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 7, Page 1403-1426, July 2026.
ABSTRACT Snakebite envenomation is a major public health concern, particularly in low‐ and middle‐income regions where access to safe and effective antivenoms is limited. Traditional antivenoms, derived from immunization with crude venom, often trigger adverse reactions and lack specificity against key venom components.
Hanan Maoz, Amir Elalouf
wiley   +1 more source

Polyvalent Antivenom Use and Predictors of Mortality from Paediatric Snakebite at a Tertiary Centre in Northwestern Nigeria

UMYU Journal of Microbiology Research
Snakebite envenomation is a neglected tropical disease and a significant public health concern in the tropics, especially in sub-Saharan Africa. Children are particularly vulnerable due to their smaller body mass and exposure to high-risk environments ...
Lugga, A. S., Bawa-Sani, H. G.
doaj   +1 more source