Results 51 to 60 of about 3,697 (183)

Engineering Antivenom: Research Progress and Future Directions in Snakebite Envenoming Therapy

Annals of the New York Academy of Sciences, Volume 1562, Issue 1, August 2026.
Snakebite envenoming therapy is evolving from plasma‐derived antivenoms toward rationally engineered therapeutics. Advances in toxicovenomics, structural biology, antibody engineering, computational protein design, recombinant expression, small‐molecule inhibitors, and diagnostics are enabling toxin‐centric development of safer, more effective, and ...
Andreas H. Laustsen
wiley   +1 more source

Severe Pediatric Snakebite With Coagulopathy and Compartment Syndrome: Conservative Management With Plasma Exchange

Clinical Case Reports, Volume 14, Issue 7, July 2026.
Therapeutic plasma exchange was successfully used in a child with severe snakebite envenomation complicated by refractory venom‐induced consumptive coagulopathy and suspected compartment syndrome, leading to full recovery and avoidance of surgical intervention.
Zain Mohammed Al Muqbel, Abdulrahman Al‐Majmuei, Ali Haider Ali, Naseem Yusuf Fahad, Reema Ajjawi, Amal Al Dailami, Afshan Lone, Manal Al Maskati, Nasser Mohamed Mansoor   +8 more
wiley   +1 more source

A Case of Naja atra Bite Complicated by Gas Gangrene Leading to Amputation: Pathogen and Management Lessons

Clinical Case Reports, Volume 14, Issue 7, July 2026.
Gas gangrene of the right upper limb following a Naja atra bite, with extensive skin necrosis and purulent discharge. ABSTRACT Gas gangrene after a Naja atra bite may be caused by Enterococcus faecalis from the snake's mouth, which is resistant to ceftriaxone.
Xuan Ci, Wei‐Wen Guo, Lei Yang, Yue Zhang, Zi‐Jing Liang, Jun‐Ting Huang   +5 more
wiley   +1 more source

Scrutinizing the Wallacean shortfall: global gaps in snake occurrence data across space and environment

Ecography, Volume 2026, Issue 7, July 2026.
Occurrence records are fundamental for ecological and evolutionary research, providing key information on species' geographic ranges. However, these records are often taxonomically, spatially, and temporally biased, requiring caution in their use. Here, we analysed the spatial coverage of occurrence records for over 3500 snake species worldwide to ...
Lívia Frateles, Cristina Ronquillo, Gabriel Nakamura, José Alexandre Felizola Diniz‐Filho, Richard James Ladle, Joaquín Hortal   +5 more
wiley   +1 more source

Bioinformatics‐Driven Design and Evaluation of Recombinant Multi‐Epitope Immunogens Derived From Snake Venom Toxins as Potential Antivenom Candidates

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 7, Page 1403-1426, July 2026.
ABSTRACT Snakebite envenomation is a major public health concern, particularly in low‐ and middle‐income regions where access to safe and effective antivenoms is limited. Traditional antivenoms, derived from immunization with crude venom, often trigger adverse reactions and lack specificity against key venom components.
Hanan Maoz, Amir Elalouf
wiley   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, Volume 293, Issue 13, Page 3881-3898, July 2026.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

A sensory ecology approach to understanding snakebites: Influence of sensory cues on the strike of the lancehead pitviper

Journal of Zoology, Volume 329, Issue 3, Page 237-246, July 2026.
Snakes are notable for having a broad range of predators and one of the most diverse repertoires of defensive behaviors. During heightened responses to aversive stimuli, one of the behaviors displayed is the venomous bite, particularly relevant because it triggers snakebite incidents in humans.
J. M. Alves‐Nunes, A. Fellone, R. H. Willemart, O. A. V. Marques   +3 more
wiley   +1 more source

Paracoccidioidomycosis in Brazil: 25‐Year Nationwide Trends in Mortality, Hospitalisations and In‐Hospital Deaths of a Neglected Systemic Mycosis

Tropical Medicine &International Health, Volume 31, Issue 7, Page 875-894, July 2026.
ABSTRACT Objective To analyse mortality, hospitalisations and in‐hospital mortality related to paracoccidioidomycosis (PCM) in Brazil, 2000–2024, from a spatio‐temporal and social inequalities perspective. Methods We conducted a mixed ecological study using death certificates from the Mortality Information System and hospital admissions from the ...
Anderson Fuentes Ferreira, Jorg Heukelbach, Eliana Amorim de Souza, Maria Aparecida Shikanai‐Yasuda, Lisandra Serra Damasceno, Terezinha do Menino Jesus Silva Leitão, Ziadir Francisco Coutinho, Helia Kawa, Milena Maria Alves Vasconcelos, Alberto Novaes Ramos Jr   +9 more
wiley   +1 more source

Sociodemographic, geographic and temporal patterns of snakebites in Brazil: a descriptive study, 2010-2022 [PDF]

Epidemiologia e Serviços de Saúde
Objective: To analyze snakebite accidents that occurred in Brazil between 2010 and 2022, focusing on the sociodemographic characteristics of victims, snake genus involved, seasonality, geographic distribution, degree of risk and relationship with biomes.
Gisele Dias de Freitas, Thiago Salomão de Azevedo, Anderson de Oliveira, Alec Brian Lacerda, Gabriella Pereira dos Santos, Etna Leal, Flávio Santos Dourado, Hui Wen Fan, Francisco Chiaravalloti-Neto   +8 more
doaj   +4 more sources

Inflammation induced by snake venoms optimizes envenomation

The Journal of Physiology, Volume 604, Issue 14, Page 5831-5852, 15 July 2026.
Abstract figure legend Schematic illustrating mechanisms underlying direct vascular absorption and subsequent movement of venom toxins into the tissues consequent to snakebite. A, snakebite into prey deposits venom toxins into the tissue interstitium, with the venom then causing acute inflammation primarily in venules.
Dirk F. van Helden, Neil Spratt, Peter J. Dosen, Sally A. McFadden, John Holdsworth, Daniel J Beard, Kirsten Coupland, Phillip Jobling, Todd A. Hardy, Derek R. Laver   +9 more
wiley   +1 more source