Results 71 to 80 of about 322,717 (342)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Termination of SNAP Emergency Allotments, Food Sufficiency, and Economic Hardships

, 2023
To meet the rising need for food and nutrition assistance during the pandemic in the United States, all states were approved to provide Emergency Allotments (EA) to households enrolled in the Supplemental Nutrition Assistance Program (SNAP).
Dasgupta, Kabir, Plum, Alexander
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Differences in Reported Benefits in Older Adults After Participation in a Nutrition Incentive Program

Journal of the Georgia Public Health Association, 2017
Background: A healthy food incentive program doubles the value of food stamp dollars at farmers’ markets, addressing financial barriers to healthy eating for low-income Supplemental Nutrition Assistance Program (SNAP), or food stamps, recipients.
Miranda Cook, Rachael Kane
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Effect of Fixed Distance Recording and Foot Length on Sensory Nerve Action Potential of Dorsal Sural Nerve in Normal Adults

Annals of Indian Academy of Neurology
Background and Objectives: Due to its distal location in the lower limb, the dorsal sural sensory nerve is pivotal in diagnosing early and subclinical peripheral neuropathy.
Shaikh Alpa Nasrin Samuel, Manjusha Shinde, Charu Bansal, Harshita Mangla, R Aruna, Tandra Ghosh   +5 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Is There an Association Between Supplemental Nutrition Assistance Program Participation and Elevated Body Mass Index in Women? [PDF]

, 2015
Background: The Supplemental Nutrition Assistance Program (SNAP), formerly known as the Food Stamp Program, is the largest nutrition assistance program in the United States. Its objective is to alleviate food insecurity and hunger. Women represent 28% of
Rucker, Jennifer Lauren
core   +1 more source

In vitro retention force measurement for three different attachment systems for implant-retained overdenture

The Journal of Indian Prosthodontic Society, 2016
Aim: The aim of this study is to compare the retention force of three different types of overdenture attachment systems used in implant-retained mandibular complete overdentures.
Kareem Mohammed Reda, Ibrahim Ramadan El-Torky, Mohamed Nabeel EL-Gendy   +2 more
doaj   +1 more source

Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs

Nature Methods, 2018
Molecular tools that target RNA at specific sites allow recoding of RNA information and processing. SNAP-tagged deaminases guided by a chemically stabilized guide RNA can edit targeted adenosine to inosine in several endogenous transcripts simultaneously,
P. Vogel, Matin Moschref, Qin Li, Tobias Merkle, Karthika D. Selvasaravanan, J. B. Li, Thorsten Stafforst   +6 more
semanticscholar   +1 more source