Results 81 to 90 of about 322,717 (342)
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
An ancient duplication of exon 5 in the Snap25 gene is required for complex neuronal development/function. [PDF]
PLoS Genetics, 2008 Alternative splicing is an evolutionary innovation to create functionally diverse proteins from a limited number of genes. SNAP-25 plays a central role in neuroexocytosis by bridging synaptic vesicles to the plasma membrane during regulated exocytosis ...
Jenny U Johansson +11 more
doaj +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Pteridines, 1998 First, we examined the effects of various chemical NO-donors on the cell damage in HL-60 cells. The most potent of these was S-nitroso-N-acetyl- penicillamine (SNAP).
Kojima Shuji
doaj +1 more source
Nutrition reviews, 2019 The Supplemental Nutrition Assistance Program-Education (SNAP-Ed) is the nutrition promotion component of SNAP, formerly known as food stamps. SNAP-Ed assists low-income populations in the United States improve dietary intake and reduce food insecurity ...
R. Rivera, M. Maulding, H. Eicher-Miller
semanticscholar +1 more source
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
FEBS Open Bio, EarlyView.Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
International Journal of Food Studies, 2012 Technologists and nutritionists are always looking for alternative ingredients to use in their formulations to improve functional and nutritional properties.
V.A. Barrientos +2 more
doaj +1 more source
EClinicalMedicine, 2019 Background Acetylcysteine (NAC) is effective at preventing liver injury after paracetamol overdose. The Scottish and Newcastle Anti-emetic Pre-treatment for Paracetamol Poisoning (SNAP) Study demonstrated that a 12 h NAC regimen was associated with fewer
J. Pettie +13 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Evaluation of a Pilot Nutrition Education Program Delivered by Hmong Community Health Workers (CHWs) [PDF]
Hmong Studies Journal, 2016 Many members of the Hmong population in the United States suffer from comparatively bad health. Moreover, disease prevention messaging that has traditionally been used through various media and healthcare outlets is not as successful with the Hmong as ...
Jeanette Treiber
doaj