Results 31 to 40 of about 8,482 (266)

Age- and Size- Based Reproductive Potential of Gray Snapper (Lutjanus griseus) in the Eastern Gulf of Mexico

open access: yesFishes
Relatively little is known about size- and age-based reproductive characteristics of Gray Snapper (Lutjanus griseus) despite a large recreational fishery along the west coast of Florida in the Southeastern U.S.A.
Ashley Wechsler   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Complete mitochondrial genome of brownstripe red snapper, Lutjanus vitta (Perciformes: Lutjanidae)

open access: yesMitochondrial DNA. Part B. Resources, 2018
The complete mitochondrial genome of the brownstripe red snapper, Lutjanus vitta was determined by MiSeq sequencing platform. The mitogenome of L. vitta (16,498 bp) encoded the typical 13 protein-coding genes, 22 tRNA genes, two rRNA genes, and two non ...
Sapto Andriyono   +3 more
doaj   +1 more source

Cryopreservation of mutton snapper ( Lutjanus analis) sperm [PDF]

open access: yesAnais da Academia Brasileira de Ciências, 2013
This study aimed to develop a protocol of semen cryopreservation of the mutton snapper Lutjanus analis. The interaction between three extenders ( pH 6.1; 7.8 and 8.2) , two concentrations of dimethyl sulfoxide ( DMSO, 5 and 10%) and three cooling rates ( -90; -60 and -30°C.min−1) on the sperm motility rate and motility time were analyzed by a factorial
SANCHES, EDUARDO G.   +3 more
openaire   +5 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Snappers Reproductive Biology: An Ecological and Aquacultural Approach

open access: yesFishes
Reproductive biology is fundamental for understanding fish population dynamics and for guiding fisheries management and aquaculture practices.
Josué López-Cardiel   +4 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Epstein Barr Virus: Development of Vaccines and Immune Cell Therapy for EBV-Associated Diseases

open access: yesFrontiers in Immunology, 2021
Epstein-Barr virus (EBV) is the first human tumor virus discovered and is strongly implicated in the etiology of multiple lymphoid and epithelial cancers.
Xinle Cui   +3 more
doaj   +1 more source

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