Results 141 to 150 of about 54,833 (248)
Advanced Science, EarlyView.FemXpress is a computational tool that leverages X‐linked single nucleotide polymorphisms (SNPs) to group cells by the origin of the inactivated X chromosome in female single‐cell RNA sequencing (scRNA‐Seq) data. It demonstrates strong performance on both simulated and real datasets without requiring parental genomic information, and can also identify ...
Xin Wang +15 more
wiley +1 more source
Sodium Nitroprusside (SNP) Obtunds The Vasopressor Action Of 5-Hydroxytrptamine (5-HT) On The Placental Intravillous Circulation [PDF]
, 2000 J. W. Downing +5 more
openalex +1 more source
Co‐Selection of Low Cadmium Accumulation and High Yield During Tomato Improvement
Advanced Science, EarlyView.This study finds that large‐fruited tomatoes accumulate less cadmium (Cd) compared to wild tomatoes and cherry tomatoes. This is because, during the improvement process of tomato, the low‐Cd allele LCT1A and the large fruit allele fw3.2T are closely linked, leading to a co‐selection event.
Xingyu Zhang +11 more
wiley +1 more source
GmSop20 Functions as a Key Coordinator of the Oil‐To‐Protein Ratio in Soybean Seeds
Advanced Science, EarlyView.This study investigates the seed oil‐to‐protein ratio as a comprehensive quality metric and identifies GmSop20 as a crucial regulatory gene through forward genetics methodologies. By integrating GmSop20 with superior haplotypes and using gene editing/overexpression, new strategies are provided for precisely tuning the seed oil‐to‐protein ratio, thereby
Haowei Zheng +17 more
wiley +1 more source
Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment
Advanced Science, EarlyView.Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu +7 more
wiley +1 more source
Manipulating Unisexual–Sexual Reproduction Transition to Engineer Genome‐Reconstructed Polyploids
Advanced Science, EarlyView.This study developed an efficient approach to generate genome‐reconstructed polyploids involving unisexual gynogenetic Carassius gibelio, sexual C. auratus, and sexual C. cuvieri. The selected superior clone inherited gynogenesis ability of C. gibelio and herpesvirus resistance of wild C.
Meng Lu +9 more
wiley +1 more source
The Current Revolution: SNPs and Chips in Molecular Diagnostics November 16–18, 2000 [PDF]
, 2000 openalex +1 more source
Advanced Science, EarlyView.Genome‐wide analyses indicate that reduced ventral diencephalon and thalamus volumes, along with decreased functional connectivity within the triple network (DMN/CEN/SN), are uniquely associated with the risk of major depression (MD) onset, compared to other similar severe psychiatric disorders.
Ming‐Min Xu +7 more
wiley +1 more source
High-Throughput SNP Genotyping by Allele-Specific PCR with Universal Energy-Transfer-Labeled Primers [PDF]
, 2001 Maxim V. Myakishev +3 more
openalex +1 more source