Results 181 to 190 of about 293,293 (239)

Genetics of retroactive measures of stress response in pigs before and after exposure to a disease challenge. [PDF]

open access: yesG3 (Bethesda)
Kayondo F   +11 more
europepmc   +1 more source

Sequential, chromosome‐specific glutamine synthetase double knockout with Cas‐CLOVER establishes enhanced CHO platforms for cell line development

open access: yesBiotechnology Progress, EarlyView.
This study established the first creation of a commercially available double GS knockout (DKO) from a single KO in CHO‐K1 cells, called CleanCut GS CHO using Cas‐CLOVER. When combined with the Harbor‐IN transposase system, CleanCut GS CHO cells demonstrated a highly antibody productivity.
Cintia Gomez Limia   +7 more
wiley   +1 more source

Effect of the rs7858836 Single-Nucleotide Polymorphisms of the ASTN2 Gene on Pain-Related Phenotypes in Japanese Women Who Underwent Laparoscopic Gynecologic Surgery. [PDF]

open access: yesNeuropsychopharmacol Rep
Inoue R   +9 more
europepmc   +1 more source

Wurtzite‐Chalcopyrite Crystal Polymorphism in CuGaS2 Nanoparticles Dictates the Localized Surface Plasmon Resonance

open access: yesChemistry – A European Journal, EarlyView.
Crystal phase‐ and size‐selective synthesis of chalcopyrite and wurtzite‐type CuGaS2 NPs was successfully achieved. They exhibited clear LSPR in the NIR region. The extinction coefficient of chalcopyrite was three times higher than that of wurtzite due to its greater symmetry and dipole moment. These results will enable precise control of the plasmonic
Keito Sano   +2 more
wiley   +1 more source

Predicting cervical cancer DNA methylation from genetic data using multivariate CMMP

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract Epigenetic modifications link the environment to gene expression and play a crucial role in tumour development. DNA methylation, in particular, is gaining attention in cancer research, including cervical cancer, the focus of this study.
Hang Zhang   +5 more
wiley   +1 more source

Pharmacogenomics of Major Depressive Disorder in Indigenous Amazonian Populations

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Major depressive disorder is a highly prevalent psychological disorder worldwide and its main treatment is the use of Selective Serotonin Reuptake Inhibitors. However, few studies have demonstrated the relationship between the presence of genetic variants in pharmacogenes and the efficacy of these drugs, especially in populations with a unique genetic ...
Kaio Evandro Cardoso Aguiar   +9 more
wiley   +1 more source

Causal Effects of Hydrophilic Bile Acids on Carfilzomib‐Related Cardiovascular Events in Multiple Myeloma: A Mendelian Randomization Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Carfilzomib is highly effective in the treatment of multiple myeloma, but it has been associated with cardiovascular adverse events that impact patient outcomes. Our prior global metabolomic analyses indicated an association between hydrophilic bile acids and carfilzomib‐cardiotoxicity risk, although a causal relationship remained to be determined ...
Samia Shabnaz   +15 more
wiley   +1 more source

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