Results 321 to 330 of about 593,238 (360)

Accurate and Efficient Detection of Nasopharyngeal Carcinoma Using Multi‐Dimensional Features of Plasma Cell‐Free DNA

Head &Neck, EarlyView.
ABSTRACT Background The incidence of Nasopharyngeal carcinoma (NPC) is rising in recent years, especially in some non‐developed parts of the world. Hence, cost‐efficient means for sensitive detection of NPC are vital. Methods We recruited 646 participants, including healthy individuals, patients with benign nasopharyngeal diseases, and NPC patients for
Song Zhang, Jiahui Tang, Pin Cui, Weihuang He, Xiaohui Lin, Shubing Wang, Yuanxian Liu, Xiaohua Tan, Shu Xu, Mingji Feng, Hanming Lai   +10 more
wiley   +1 more source

Combining Clinical, Genetic and Protein Markers Using Machine Learning Models Discriminates Psoriatic Arthritis Patients From Those With Psoriasis. [PDF]

J Psoriasis Psoriatic Arthritis
Ganatra D, Kotlyar M, Dohey A, Codner D, Li Q, Abji F, Rasti M, Eder L, Gladman D, Rahman P, Jurisica I, Chandran V.   +11 more
europepmc   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Identification of loci associated with women's reproductive traits and exploration of a shared genetic basis with obesity. [PDF]

Hum Genomics
Kwon SA, Cho YS.
europepmc   +1 more source

Mechanisms of enhancer‐driven oncogene activation

International Journal of Cancer, EarlyView.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend, Ruud Delwel, Dorien Pastoors   +2 more
wiley   +1 more source

Comprehensive genetic and epigenetic characterization of Lynch‐like syndrome patients

International Journal of Cancer, EarlyView.
What's New? Lynch‐like syndrome is associated with development of colorectal cancer (CRC) with microsatellite instability and loss of expression of certain mismatch repair (MMR) genes, similar to Lynch syndrome, but unlike Lynch syndrome, the genetic cause of Lynch‐like syndrome (LLS) remains unknown.
Francesca Pirini, Luciano Calzari, Gianluca Tedaldi, Michela Tebaldi, Valentina Zampiga, Ilaria Cangini, Rita Danesi, Mila Ravegnani, Valentina Arcangeli, Alessandro Passardi, Elisabetta Petracci, Sara Bravaccini, Giorgia Marisi, Alessandra Viel, Daniela Barana, Monica Pedroni, Luca Roncucci, Daniele Calistri, Davide Gentilini   +18 more
wiley   +1 more source

ARMSprimer3: An open-source primer design Python program for amplification refractory mutation system PCR (ARMS-PCR). [PDF]

J Pathol Inform
Guo J, Grojean J, Guo H.
europepmc   +1 more source

Whole‐genome sequencing of 1,083 HPV45 cases and controls identifies genetic variants associated with glandular cervical lesions

International Journal of Cancer, EarlyView.
What's New? Little is known about how genetic variation in human papillomavirus type 45 (HPV45) influences its ability to cause cancer. Here, the authors conducted the largest whole‐genome sequencing study to date of HPV45, looking for associations between viral genetic variation and precancer or cancer risk.
Aimee J. Koestler, Chase W. Nelson, Meredith Yeager, Zigui Chen, Sambit K. Mishra, Laurie Burdett, Michael Dean, Elizabeth Suh‐Burgmann, Thomas Lorey, Gary M. Clifford, Nicolas Wentzensen, Philip E. Castle, Mark Schiffman, Robert D. Burk, Lisa Mirabello   +14 more
wiley   +1 more source

A Systematic Review of the Effect of Gene-Lifestyle Interactions on Metabolic-Disease-Related Traits in South Asian Populations. [PDF]

Nutr Rev
Bineid MM, Ventura EF, Samidoust A, Radha V, Anjana RM, Sudha V, Walton GE, Mohan V, Vimaleswaran KS.   +8 more
europepmc   +1 more source

Deciphering dual clinical entities associated with TP53 pathogenic variants: Insights from 53,085 HBOC panel analyses in French laboratories

International Journal of Cancer, EarlyView.
What's New? TP53 is included in most cancer predisposition multigene panels, but analyzing the contribution of TP53 variants to cancer predisposition beyond the Li–Fraumeni syndrome remains challenging. This study, based on 53,085 hereditary breast and ovarian cancer panel analyses, explores the genotype–phenotype correlation of TP53 variants and ...
Edwige Kasper, Flavie Boulouard, Noémie Basset, Lisa Golmard, Hella Sassi, Emilie Bouvignies, Maud Branchaud, Camille Charbonnier, Nathalie Parodi, Marion Rolain, Juliette Albuisson, Ayman al Saati, Patrick Benusiglio, Pascaline Berthet, Marie Bidart, Céline Bonnet, Ahmed Bouras, Nadia Boutry‐Kryza, Fanny Brayotel, Virginie Bubien, Adrien Buisson, Laurent Castéra, Olivier Caron, Chrystelle Colas, Florence Coulet, Capucine Delnatte, Valentin Derangère, Alice Fievet, Céline Garrec, Marion Gauthier‐Villars, Mathilde Gay‐Bellile, Vincent Goussot, Jessica le Gall, Mathis Lepage, Anna Lokchine, Alexandre Perrier, Etienne Rouleau, Nicolas Sevenet, Dominique Stoppa‐Lyonnet, Jean‐Marie Ravel, Pierre Vande Perre, Dominique Vaur, Paul Vilquin, Gaëlle Bougeard, Stéphanie Baert‐Desurmont, Jean‐Christophe Thery, Claude Houdayer   +46 more
wiley   +1 more source