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SNPs on Chips: The Hidden Genetic Code in Expression Arrays

Biological Psychiatry, 2007
Gene expression microarray analysis in postmortem brains is one of the fastest growing fields of psychiatric research. Here we show that common polymorphisms (SNPs) present on probe sets can masquerade as significant "gene expression" differences. After first observing this artifact in the Catechol-O-methyl transferase (COMT) gene, we replicate the ...
Edward G. Jones   +10 more
openaire   +3 more sources

Estimation of Missing Values in SNP Array

2014
DNA microarray usage in genetics is rapidly proliferating, generating huge amount of data. It is estimated that around 5-20% of measurements do not succeed, leading to missing values in the data destined for further analysis. Missing values in further microarray analysis lead to low reliability, therefore there is a need for effective and efficient ...
openaire   +2 more sources

Use of SNP-Arrays for ChIP Assays: Computational Aspects

2009
The simultaneous genotyping of thousands of single nucleotide polymorphisms (SNPs) in a genome using SNP-Arrays is a very important tool that is revolutionizing genetics and molecular biology. We expanded the utility of this technique by using it following chromatin immunoprecipitation (ChIP) to assess the multiple genomic locations protected by a ...
Enrique M. Muro   +3 more
openaire   +3 more sources

A 55 K SNP array-based genetic map and its utilization in QTL mapping for productive tiller number in common wheat

Theoretical and Applied Genetics, 2018
Jiajun Liu   +16 more
semanticscholar   +1 more source

Development of an Axiom Sugarcane100K SNP array for genetic map construction and QTL identification

Theoretical and Applied Genetics, 2019
Qian You   +8 more
semanticscholar   +1 more source

Exploring the cause of early miscarriage with SNP-array analysis and karyotyping

Journal of Maternal-Fetal & Neonatal Medicine, 2019
S. Qu   +6 more
semanticscholar   +1 more source

Clinical application of SNP array analysis in first‐trimester pregnancy loss: a prospective study

Clinical Genetics, 2017
Y. Wang   +11 more
semanticscholar   +1 more source

Rapid identification of an adult plant stripe rust resistance gene in hexaploid wheat by high-throughput SNP array genotyping of pooled extremes

Theoretical and Applied Genetics, 2017
Jianhui Wu   +8 more
semanticscholar   +1 more source

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