Results 141 to 150 of about 215,087 (323)

Brief introduction in phenotypic and genetic differences of C57BL/6 and BALB/c mice substrains

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This article briefly reviews the origin, differentiation, and phenotypic and genetic differences between the C57BL/6 and BALB/c mouse substrains. Abstract Experimental mice play a critical role in biomedical research. The phenotype and application of different substrains vary due to genetic differentiation and variation.
Lan Zhao, Jie Wei, Bingfei Yue
wiley   +1 more source

Honey Bee Breeding and Breed: Advancements, Challenges, and Prospects

open access: yesAnimal Research and One Health, EarlyView.
Our work clarifies concepts related to honey bee classification, reviews traditional and modern breeding techniques, explores advancements in molecular breeding, prospects gene‐editing tools, and advocates for integrated breeding strategies to ensure the long‐term sustainability and vitality of honey bee populations amid declining managed populations ...
Zheguang Lin   +5 more
wiley   +1 more source

SNP genotyping in the β2-adrenergic receptor by electronic microchip assay, DHPLC, and direct sequencing [PDF]

open access: bronze, 2002
N. Yoshida   +7 more
openalex   +1 more source

Shennong 1 Chicken 40K Liquid Chip: Advancing Genetic Research in Chinese Indigenous Chickens

open access: yesAnimal Research and One Health, EarlyView.
Based on comprehensive genomic data of Chinese indigenous chickens, we developed a specialized genotyping array for this population. Comparative analyses with published mainstream arrays and evaluations, including genetic assessment of diverse chicken types and gene mining analyses, demonstrated its superior applicability to Chinese indigenous chickens.
Chaoqun Gao   +14 more
wiley   +1 more source

Comparative Effectiveness of Abatacept versus Adalimumab in Shared Epitope positive and negative Rheumatoid Arthritis patients

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives The effect of the shared epitope (SE), and valine at position 11 (Val11) of HLA‐DRB1, on the activation of CD4+ T cells, is expected to be diminished by abatacept, a co‐stimulation blocker. However, published evidence on the value of genetic stratification for abatacept treatment is conflicting.
Chuan Fu Yap   +14 more
wiley   +1 more source

GenoTriplo: A SNP genotype calling method for triploids

open access: yesPLOS Computational Biology
AbstractTriploidy is very useful in both aquaculture and some cultivated plants as the induced sterility helps to enhance growth and product quality, as well as acting as a barrier against the contamination of wild populations by escapees. To use genetic information from triploids for academic or breeding purposes, an efficient and robust method to ...
Roche Julien   +6 more
openaire   +4 more sources

Alu Overexpression Leads to an Increased Double‐stranded RNA Signature in Dermatomyositis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Dermatomyositis is an autoimmune condition characterized by a high interferon signature of unknown etiology. Because coding sequences constitute <1.2% of our genomes, there is a need to explore the role of the non‐coding genome in disease pathogenesis.
Rayan Najjar   +2 more
wiley   +1 more source

Comparison of GenFlex Tag Array and Pyrosequencing in SNP Genotyping [PDF]

open access: bronze, 2003
Daniel C. Chen   +5 more
openalex   +1 more source

Credibility of genetic predictors for antiepileptic drug resistance: A systematic Bayesian reappraisal of published meta‐analyses

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
We systematically reappraised meta‐analyses of pharmacogenetic studies to evaluate the credibility of association between gene polymorphisms and resistance to anti‐epileptic drugs (AEDs). A systematic search was performed in PubMed, Web of Knowledge, Cochrane Library and OpenGrey up to April 2025.
Martina Giacon   +2 more
wiley   +1 more source

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