Results 281 to 290 of about 220,745 (323)

Mendelian Randomization Analysis of the Causal Link Between Rheumatoid Arthritis and Interstitial Lung Disease

Respirology, EarlyView.
This Mendelian randomization study provides genetic evidence supporting a causal effect of rheumatoid arthritis on the risk of interstitial lung disease, highlighting potential shared mechanisms between autoimmune arthritis and pulmonary fibrosis. ABSTRACT Background and Objectives Rheumatoid arthritis (RA) is a systemic autoimmune disease that is ...
Mengyu Zhang, Xiao Chen, Wenqing Zhang, Guang Yang, Yunhong Yin, Yiqing Qu   +5 more
wiley   +1 more source

Whole‐genome paternal uniparental disomy identified through prenatal single‐nucleotide polymorphism‐based cell‐free DNA screening

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective Prenatal single‐nucleotide polymorphism (SNP)‐based cell‐free DNA (cfDNA) screening can identify genome‐wide paternal uniparental disomy (GW‐UPDpat), including cases with complete hydatidiform mole with a coexisting fetus (CHMCF), those with placental mesenchymal dysplasia (PMD) and those with a mosaic/chimeric GW‐UPDpat syndrome ...
P. Benn, K. Hashimoto, V. Souter, R. Dhamankar, W. Xu, D. Kijacic   +5 more
wiley   +1 more source

Identification of SNPs and candidate genes associated with first egg weight in laying hens based on whole-genome genotyping data

Н. А. Волкова, А. Н. Ветох   +1 more
openalex   +2 more sources

Development of Microsatellite Markers for Ex Situ Management of the Harpy Eagle Using Next Generation Sequencing

Zoo Biology, EarlyView.
ABSTRACT The Harpy Eagle (Harpia harpyja), one of the largest birds of prey in the world, is threatened with extinction throughout its entire area of occurrence in the Neotropics. While conservation efforts for the wild populations are crucial, it is also important to focus on ex situ conservation actions.
Mylena Kaizer, Pedro S. Bittencourt, Érico M. Polo, Tânia M. Sanaiotti, Izeni P. Farias, Lorenzo von Fersen, Tomas Hrbek, Aureo Banhos   +7 more
wiley   +1 more source

Avian extra‐pair paternity in the last European primeval forest

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Primeval forests offer a reference baseline to understand the origins and evolution of mating systems, as their relatively undisturbed environment provides a glimpse into how ecological interactions and natural selection play out in their original context.
Joanna Sudyka, Irene Di Lecce, Grzegorz Hebda, Patryk Rowiński, Robert Rutkowski, Anna Szczuka, Charles Perrier, Marta Cholewa, Marta Maziarz, Tomasz Wesołowski, Marta Szulkin   +10 more
wiley   +1 more source

Early life exploration behaviour and life‐history loci are colocalized in an adaptive genomic hotspot in Atlantic salmon

Journal of Animal Ecology, EarlyView.
The genetic architecture of phenotypic correlations offers insights into how natural selection operates in the wild. Two functional phenotypes in Atlantic salmon, early life exploration and age‐at‐maturity, are correlated at an adaptive genomic hotspot, but through distinct genetic markers (SNPs), ruling out causality.
Tutku Aykanat, Jaakko Erkinaro
wiley   +1 more source

Polygenic Risk for Pre‐Eclampsia and the Long‐Term Risk of Incident Hypertension and Cardiovascular Disease: A Population‐Based Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To investigate whether genetic predisposition to pre‐eclampsia (PE), measured by a polygenic risk score (PRS), is associated with incident hypertension and cardiovascular disease (CVD) after delivery in Asian women. Design Prospective population‐based cohort study.
Eun‐Saem Choi, Sang‐Hyuk Jung, Young Mi Jung, Chan‐Wook Park, Joong Shin Park, Jong Kwan Jun, Jaeyoung Kim, Beomsu Kim, Chamlee Cho, Injeong Shim, Dokyoon Kim, Hong‐Hee Won, Seung Mi Lee   +12 more
wiley   +1 more source

Generalisability of Maternal Genetic Risk Score for Birth Weight Across Racial Identity and Ancestry: A Secondary Analysis of a Prospective Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Maternal genotypes may be useful to customise foetal growth assessment, but generalisability across diverse racial and ancestral groups remains uncertain. We assessed the generalisability of a genetic risk score for birth weight (GRSBW), derived from participants of predominantly European ancestry, within a diverse U.S.
Bita Tristani‐Firouzi, Lisa Pappas, Merry Joseph, Maryam Zeinomar, Michelle P. Debbink, Joseph Mims, Rafael Guerrero, Barry Moore, Robert M. Silver, Tsegaselassie Workalemahu, David Haas, Jonathan G. Steller, George Saade, Nathan R. Blue   +13 more
wiley   +1 more source

Implications of uniparental disomy in forensic kinship testing: A case study of paternal isodisomy on chromosome 3

Journal of Forensic Sciences, EarlyView.
Abstract In typical inheritance, a child receives one chromosome of each pair from each parent. In rare cases, however, both chromosomes may be inherited from the same parent, a phenomenon known as uniparental disomy (UPD). In forensic kinship testing, UPD can lead to Mendelian inconsistencies between parent and child, increasing the risk of ...
Hannah Fontanil, Sharlize Pedroza Matute, Thomas Haizel, Sasitaran Iyavoo   +3 more
wiley   +1 more source