Results 291 to 300 of about 219,632 (346)

Detecting SARS-CoV-2 variants with SNP genotyping

, 2020
Harper H, Burridge AJ, Winfield M, Finn A, Davidson AD, Matthews D, Hutchings S, Vipond B, Jain N, Edwards KJ, The COVID-19 Genomics UK (COG-UK) consortium, Barker G.   +11 more
europepmc   +1 more source

Genomic Investigations Unveil the Genetic Underpinnings of Environmental Adaptation in African Goat Populations

Integrative Zoology, EarlyView.
This study integrates genomics and landscape genetics to analyze African goat environmental adaptation. Analyzing 1591 samples, it finds population structure differentiates geographically into four groups, with gene flow between wild Yura goats and North Africans.
Weifeng Peng, Yihua Wang, Yiyuan Zhang, Lei Gao, Lili Wu, Shuping Wang, Yiyang Gao, Wanlu Shi, Kaixin Lu, Rong Deng, Junting Li, Jing Han, Xiaohui Lu, Yujie Liu, Xiaojiao Tang, Yunxia Zhang, Guoyin Li, Li Huang, Mingsheng Yang, Xiaoyan Li   +19 more
wiley   +1 more source

Geographic Patterns of Head Morphology in Syngnathus typhle Across Marine Regions

Integrative Zoology, EarlyView.
Morphometric analysis of Syngnathus typhle head shape shows distinct geographic patterns across Baltic, North, Atlantic, and Mediterranean marine regions, driven by variation in snout length, head depth, and eye position. Findings provide a non‐invasive baseline for conservation monitoring.
Miriam Ravisato, Glenn Le Floch, Cataldo Pierri, Vincent Bels, José J. Castro‐Hernandez, Raphael Cornette, Luca Giannattasio, Michele Gristina, Airam Guerra, Charlotta Kvarnemo, Tamara Lazic, Patrick Louisy, Nuno Monteiro, Bruno Serranito, Marco Spoto, Beatriz Staboada, Eric Feunteun   +16 more
wiley   +1 more source

Microhaplotype Methods Enable Relationship Inference in a Bottlenecked Mammalian Species

Animal Conservation, EarlyView.
Northern elephant seals (Mirounga angustirostris) are among the most genetically depauperate mammals in the world. A near‐total population bottleneck in the 19th century, coupled with the breeding system of extreme polygyny, has challenged efforts to estimate individual reproductive success with genetic methods.
Keith M. Hernandez, Anthony J. Clemento, Juliette E. Linossier, Daniel E. Crocker, Daniel P. Costa, Colleen Reichmuth, John Carlos Garza   +6 more
wiley   +1 more source

Relationships Between European Wildcats and Domestic Cats in an Area of Sympatry: Exploring Key Conservation Questions on Hybridization and Disease Transmission

Animal Conservation, EarlyView.
We have found evidence of behavioural barriers for both hybridization and disease transmission between European wildcats and domestic cats. This includes hierarchical interspecies exclusion enforced by wildcats, as well as sexual selection exerted by wildcat females.
Jose María Gil‐Sánchez, Elena Bertos, Mariola Sánchez‐Cerdá, Emilio Virgós, Marcos Moleón   +4 more
wiley   +1 more source

Genotyping USA Laboratory-Maintained Isolates and European Clinical Isolates of Dirofilaria Immitis to Assess Macrocyclic Lactone Susceptibility or Resistance at Predictive Snp Sites Using Droplet Digital Pcr

Sohini Kumar, Hua Che, R Chiummo, Lea Heuer, Carolin V. Schneider, Margaret Werr, Frank Guerino, Elias Papadopolous, Αnastasia Diakou, Andrei Daniel Mihalca, Donato Traversa, Angela Di Cesare, Thavy Long, Roger K. Prichard   +13 more
openalex   +1 more source

Mediation of Polygenic Asthma Risk Through Gene Expression

Allergy, EarlyView.
We apply published PRSs in African‐ancestry individuals and quantify the extent to which the PRS‐asthma relationship is mediated by clinical biomarkers and gene‐expression signatures of asthma. We found the best PRS to be the one derived using the largest sample size and including African‐ancestry individuals.
Rakesh Natarajan, Brooke Szczesny, Kanika Kanchan, Erika Esquinca, Meher Preethi Boorgula, Sameer Chavan, Monica Campbell, Wendy Lorizio, Ayo P. Doumatey, Alvaro A. Cruz, Harold Watson, Edward T. Naureckas, B. Louise Giles, Ganiyu Arinola, Olumide Sogaolu, Adegoke G. Falade, Nadia N. Hansel, Christopher O. Olopade, Charles N. Rotimi, R. Clive Landis, Camila A. Figueiredo, Eimear E. Kenny, Ingo Ruczinski, Andrew H. Liu, Carole Ober, Margaret A. Taub, Randi K. Johnson, Kathleen C. Barnes, Genevieve L. Wojcik, Rasika A. Mathias   +29 more
wiley   +1 more source

Comorbid Chronic Rhinosinusitis and Asthma: Shared Risk Factors and Treatment Implications—An EAACI Task Force Report

Allergy, EarlyView.
ABSTRACT Chronic rhinosinusitis (CRS) and asthma are prevalent conditions that often coexist. These diseases share common inflammatory mechanisms, such as T‐helper cell 2 (T2)‐high inflammation, driven by interleukin (IL)‐4, IL‐5, and IL‐13 cytokines.
Sanna Toppila‐Salmi, Sietze Reitsma, Valérie Hox, Simon Gane, Philippe Gevaert, Juan Maza‐Solano, Alma Helevä, Ida Sulku, Kaisa Santala, Iiris Kangasniemi, Ludger Klimek, Adam Chaker, Aspasia Karavelia, Michael Rudenko, Oliver Pfaar, Laura Van Gerven, Shaari Ariana, Michele Schiappoli, Marie Lundberg, Jan Hagemann, Ibon Eguíluz‐Gracia, Andre Moreira   +21 more
wiley   +1 more source

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Amplifluor-Based SNP Genotyping

2023
Amplifluor, a genotyping system used to analyze single nucleotide polymorphisms (SNPs), is supplied by Merck-Millipore. Amplifluor is based on polymerase chain reaction (PCR) with two competing allele-specific primers and a SNP specific common reverse primer.
Manmode Darpan, Mohanrao, Senapathy, Senthilvel, Yarabapani Rushwanth, Reddy, Chippa Anil, Kumar, Palchamy, Kadirvel   +4 more
openaire   +2 more sources

Techniques patents for SNP genotyping

Pharmacogenomics, 2003
Single nucleotide polymorphisms (SNPs) are the most abundant form of genetic variation in the human genome, accounting for more than 90% of all differences between individuals. Many complex phenotypes in humans have a significant genetic component and most of the variability is therefore likely to stem from differences in patterns of SNPs.
Richard M, Twyman, Sandy B, Primrose
openaire   +2 more sources