Results 311 to 320 of about 223,459 (323)

Assessment of two flexible and compatible SNP genotyping platforms: TaqMan® SNP Genotyping Assays and the SNPlex™ Genotyping System

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2005
In this review we describe the principles, protocols, and applications of two commercially available SNP genotyping platforms, the TaqMan SNP Genotyping Assays and the SNPlex Genotyping System. Combined, these two technologies meet the requirements of multiple SNP applications in genetics research and pharmacogenetics.
Francisco M, De la Vega, Katherine D, Lazaruk, Michael D, Rhodes, Michael H, Wenz   +3 more
openaire   +2 more sources

Missing SNP Genotype Imputation

2011
High-throughput single nucleotide polymorphism (SNP) genotyping technologies conveniently produce large SNP genotype datasets for genome-wide linkage and association studies. Various factors, from array design and hybridization, can give rise to a certain percentage of missing calls, and the problem becomes severe when the target organisms such as ...
openaire   +1 more source

The TaqMan Method for SNP Genotyping

2009
Single nucleotide polymorphisms (SNPs) are common DNA sequence variations that occur at single bases within the genome. SNPs have been instrumental in elucidating the genetic basis of common, complex diseases using genome-wide association studies, candidate gene case-control association studies, and genome-wide linkage analyses.
Gong-Qing, Shen, Kalil G, Abdullah, Qing Kenneth, Wang   +2 more
openaire   +2 more sources

[Approaches for SNP genotyping].

Yi chuan = Hereditas, 2009
With the completion of the Human Genome Project (HGP), typing single nucleotide polymorphisms (SNP) has become one of the main tasks in the post-genome era. Consequently, a robust, flexible and cost-effective technique for SNP typing is essential to analyze a large number of SNPs.
Wei-Peng, Wang, Kun-Yi, Ni, Guo-Hua, Zhou   +2 more
openaire   +1 more source

Machine Learning-Based Imputation of Missing SNP Genotypes in SNP Genotype Arrays

2013
The missing value problem in SNP genotype data sets is introduced along with a short overview of two commonly used imputation algorithms, fastPHASE and KNNimpute, used to resolve the missing value problem for such data sets. A comparison of the two algorithms is provided with additional preliminary biological and mathematical background information for
openaire   +1 more source

Medium-Throughput SNP Genotyping Using Mass Spectrometry: Multiplex SNP Genotyping Using the iPLEX® Gold Assay

2010
Depending on the scope of the research project, categories of single-nucleotide polymorphism (SNP) genotyping experiments range from low to medium to high throughput, with each approach differing widely in cost, platform, and efficiency. Medium-throughput genotyping is generally appropriate for assaying up to 36 markers in 384 individuals and is ...
openaire   +2 more sources

Genotyping SNPs With Molecular Beacons

2003
Salvatore A E, Marras, Fred Russell, Kramer, Sanjay, Tyagi   +2 more
openaire   +2 more sources

Invader Assay for SNP Genotyping

2003
Victor, Lyamichev, Bruce, Neri
openaire   +2 more sources

SNP Genotyping Techniques

2006
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Pyrosequencing for SNP Genotyping

2003
openaire   +2 more sources