Results 231 to 240 of about 524,252 (269)

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng, Xiao Han, Congquan Wu, Qiaowen Lu, Shujun Gao   +4 more
wiley   +1 more source

Comprehensive analysis of the deleterious nonsynonymous, non-coding SNPs and cancer variants of human aldo-keto reductase type 1 (AKR1C1) protein and their probable association with disease risk and progression: a computational study. [PDF]

Biochem Biophys Rep
Nila NN, Mishu ID, Mahmud Z, Tamanna S, Fahima K, Khan AS, Ansari F, Hossain M, Howlader MZH.   +8 more
europepmc   +1 more source

Causal effects of reproductive traits on cognitive function: A two‐sample and multivariable mendelian randomization study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Potential associations between reproductive traits and cognitive function have been discovered; however, the results are inconsistent, and the causalities are unclear. This study utilized Mendelian randomization (MR) analysis to assess the causal impact of reproductive traits on cognitive function.
Xia Wang, Yunyun Guo
wiley   +1 more source

SNP calling, haplotype phasing and allele-specific analysis with long RNA-seq reads. [PDF]

Nat Methods
Huang N, Li H, Human Pangenome Reference Consortium.   +2 more
europepmc   +1 more source

The importance of gene polymorphism in familial inheritance of endometriosis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The study aimed to investigate familial transmission patterns in women with endometriosis by generating a customized single‐nucleotide polymorphism (SNP) array. Methods Patients aged 18–45 who were diagnosed histopathologically with endometriosis were included in the study.
Hale Goksever Celik, Candan Eker, Berivan Guzelbag, Ercan Bastu, Tuba Gunel   +4 more
wiley   +1 more source

The genetic architecture of human cerebellar morphology supports a key role for the cerebellum in human evolution and psychopathology. [PDF]

Commun Biol
Moberget T, van der Meer D, Bahrami S, Roelfs D, Frei O, Kaufmann T, Fernandez-Cabello S, Kim M, Wolfers T, Diedrichsen J, Smeland OB, Shadrin A, Dale A, Andreassen OA, Westlye LT.   +14 more
europepmc   +1 more source

Socioeconomic Status Modifies the Risk of Gastric Cancer Through Metabolomic Signature: Evidence From a Prospective Cohort Study

iNew Medicine, EarlyView.
ABSTRACT The role of metabolites in the association between socioeconomic status (SES) and gastric cancer remains unclear. This study seeks to elucidate the role of metabolomics in the association between SES and gastric cancer, as well as to explore potential interactions between metabolic signatures and polygenic risk score (PRS) in the context of ...
Shiyin Meng, Shangxin Zhang, Jing Wang, Zhuoyi Wu, Wenjie Xuan, Jiawei Zhang, Qihong Zhao, Anla Hu, Jing Ni   +8 more
wiley   +1 more source

Impact of control selection strategies on GWAS results: a study of prostate cancer in the UK Biobank. [PDF]

Brief Bioinform
Lu J, Thygesen JH, Beaumont RN, Weedon MN, Green HD.   +4 more
europepmc   +1 more source

The <i>Tofu</i> Mutation Restores Female Fertility to <i>Drosophila</i> with a Null <i>BEAF</i> Mutation. [PDF]

Genes (Basel)
McKowen JK, Dassanayake M, Hart CM.
europepmc   +1 more source

Probabilities of two alleles being identity by state at unobserved loci predicted by observed loci in cattle populations. [PDF]

Sci Rep
Nagai R, Honda T, Satoh M, Uemoto Y.
europepmc   +1 more source