Results 21 to 30 of about 8,567 (186)

Clinical and Neurocognitive Predictors of Functional Outcome in Depressed Patients with Partial Response to Treatment: One Year Follow-Up Study

Neuropsychiatric Disease and Treatment, 2020
Sabrina Castellano,1 Carla Torrent,2 Maria Cristina Petralia,3 Justyna Godos,4 Rita Anna Cantarella,5 Andrea Ventimiglia,6 Simona De Vivo,6 Silvia Platania,1 Maria Guarnera,7 Concetta Pirrone,1 Filippo Drago,4 Eduard Vieta,2 Santo Di Nuovo,1 Dina Popovic,
Castellano S, Torrent C, Petralia MC, Godos J, Cantarella RA, Ventimiglia A, De Vivo S, Platania S, Guarnera M, Pirrone C, Drago F, Vieta E, Di Nuovo S, Popovic D, Caraci F   +14 more
doaj  

Serotonin Noradrenaline Reuptake Inhibitors (SNRIs) [PDF]

, 2012
Antidepressants that block the reuptake of serotonin (5-HT) and noradrenaline (NA) are called 5-HT and NA reuptake inhibitors (SNRIs). SNRIs are agents that show “dual action” on 5-HT and NA. These drugs bind the 5-HT transporters (SERT) and NA transporters (NAT) similar to tricyclic antidepressants (TCAs). However, SNRIs differ from TCAs in that SNRIs
Celikyurt, Ipek Komsuoglu, Mutlu, Oguz, Ulak, Guner   +2 more
openaire   +2 more sources

Spontaneous Intracerebral Hemorrhage Due to Delta Storage Pool Disease in a Patient on a Serotonin-Norepinephrine Reuptake Inhibitor

Frontiers in Neurology, 2019
We report a case of spontaneous intracerebral hemorrhage (sICH) due to delta storage pool disease in a 60-year-old female on a serotonin-norepinephrine reuptake inhibitor (SNRI). Increased susceptibility to SNRI-effects on hemostasis was due to a genetic
Annette Leibetseder, Judith Wagner, Josef Tomasits, Hans-Peter Haring, Markus Hutterer, Johannes Trenkler, Tim J. von Oertzen   +6 more
doaj   +1 more source

Desvenlafaxine may accelerate neuronal maturation in the dentate gyri of adult male rats. [PDF]

PLoS ONE, 2014
Adult hippocampal neurogenesis has been linked to the effects of anti-depressant drugs on behavior in rodent models of depression. To explore this link further, we tested whether the serotonin-norepinephrine reuptake inhibitor (SNRI) venlafaxine impacted
Aditya Asokan, Alan R Ball, Christina D Laird, Linda Hermer, Brandi K Ormerod   +4 more
doaj   +1 more source

Trial of Preemptive Pharmacogenetic Testing in Underserved Patients (TOPP UP): Study Framework and Baseline Characteristics of Randomized Controlled Trial Participants. [PDF]

Clin Transl Sci
ABSTRACT Research in pharmacogenetics has advanced over the years, but its broad clinical implementation remains limited. While medically underserved patients may particularly benefit from preemptive pharmacogenetic testing, its clinical impact in this population has not been well explored.
Miranda AM, Lteif C, Fofanova I, Gawronski BE, Elwood EN, Norris ML, Cicali EJ, Salloum RG, Nguyen KA, Jones RE, Harrell G, Malaty JZ, Cavallari LH, Duarte JD.   +13 more
europepmc   +2 more sources

Severe, Non‐apneic Respiratory Dysfunction and Hypoxia following Generalized Convulsive Seizures

Annals of Neurology, EarlyView.
Objective Sudden unexpected death in epilepsy (SUDEP) is a devastating consequence of some generalized convulsive seizures (GCS). Recent work has focused on seizure related apnea as a biomarker of SUDEP risk, frequently without characterizing the adequacy of non‐apneic ventilation or identifying other dysfunctional breathing patterns.
Haley E. Pysick, Rup K. Sainju, Roshni Nair, Deidre N. Dragon, Eduardo Bravo, Laura Vilella, Xiaojin Li, Samden D. Lhatoo, George B. Richerson, Brian K. Gehlbach   +9 more
wiley   +1 more source

Serotonin and norepinephrine reuptake inhibitor antidepressants: a look through the prism of their 30-year history

Неврология, нейропсихиатрия, психосоматика, 2018
Based on the data available in the literature, the author has first systematized in detail the main stages of the design and clinical introduction of serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressants.
D. S. Danilov
doaj   +1 more source

Antidepressants for social anxiety disorder: A systematic review and meta‐analysis

Neuropsychopharmacology Reports, 2022
Aim This systematic review is aimed to update and reintegrate the pharmacotherapy of social anxiety disorder (SAD), including the Japanese medical database. Methods We conducted a systematic review and meta‐analysis of pharmacotherapy of SAD according to
Nobuyuki Mitsui, Yutaka Fujii, Satoshi Asakura, Hissei Imai, Hisashi Yamada, Naoki Yoshinaga, Yoshihiro Kanai, Takeshi Inoue, Eiji Shimizu   +8 more
doaj   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

British Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou, Georgia Valsami, Georgios Ismailos   +2 more
wiley   +1 more source

Antidepressants and the risk of hyponatremia: A multi‐institutional cohort study using observational medical outcomes partnership—Common Data Model

British Journal of Clinical Pharmacology, EarlyView.
Aim Hyponatremia is a common yet potentially serious adverse event associated with antidepressants. Identifying the antidepressant class with the least risk of hyponatremia would improve patient safety. Methods Using electronic medical records from 15 hospitals standardized into Observational Medical Outcomes Partnership Common Data Model (2003–2023 ...
Kyungyeon Jung, Ju Hwan Kim, Da Eun Hyeon, Jeongmoon Ji, Min Young Lee, Hayun Choi, Dong Yun Lee, Min Woo Kim, Yoonmin Jang, Seonghoon Hwang, Jaehyeong Cho, Seok Young Song, Sang Youl Rhee, Jae Myung Cha, Won‐Woo Seo, Chang‐Won Jeong, Seung‐Jin Kwag, Woo Jin Kim, Jaeuk Hwang, Min‐ho Kim, Rae Woong Park, Ju‐Young Shin   +21 more
wiley   +1 more source