Results 81 to 90 of about 9,878 (194)

Substitution Patterns After Discontinuation of CNS‐Active Medications in Older Adults in Primary Care

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Little is known about substitution of alternative medications in the context of deprescribing. The objectives were to: (1) determine the frequency of medication substitutions among those who discontinued a central nervous system (CNS)‐active medication, and (2) characterize substitutions as potentially inappropriate (as per the 2023
Shelly L. Gray, Annalisa V. Piccorelli, Laura A. Hart, Andrea J. Cook, Brian D. Williamson, Benjamin H. Balderson, Elizabeth A. Phelan   +6 more
wiley   +1 more source

Trend in SSRI-SNRI antidepressants prescription over a 6-year period and predictors of poor adherence

, 2013
PURPOSE: To describe antidepressant (AD) use in the Emilia-Romagna Region (Italy) and to evaluate adherence to treatment with selective serotonin receptor inhibitors or selective noradrenaline receptor inhibitors (SSRI-SNRI).
PICCINNI, CARLO, Clo M, DE PONTI, FABRIZIO, Sangiorgi E, TARRICONE, ILARIA, POLUZZI, ELISABETTA, MENCHETTI, MARCO   +6 more
core   +1 more source

Use of SSRI and SNRI Antidepressants during Pregnancy: A Population-Based Study from Denmark, Iceland, Norway and Sweden. [PDF]

, 2015
BackgroundThe purpose was to describe utilization of selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), including trends in prevalence, characteristics of users, drug switching and changes in ...
Nørgaard, Mette, Furu, Kari, Mette Nørgaard (65616), Unnur Valdimarsdottir (2580412), Lena Brandt (836854), Brandt, Lena, Unnur Valdimarsdottir, Helle Kieler (836853), Kieler, Helle, Zoega, Helga, Helga Zoega, Haglund, Bengt, Valdimarsdottir, Unnur, Mette Nørgaard, Lena Brandt, Kari Furu, Helle Kieler, Bengt Haglund, Bengt Haglund (836855), Kari Furu (238283), Helga Zoega (2580418)   +20 more
core   +1 more source

A systematic review and meta-analysis of randomized controlled head-to-head trials of recommended drugs for neuropathic pain

PAIN Reports
. Neuropathic pain is a challenging chronic pain condition. Limited knowledge exists regarding the relative effectiveness of pharmacological treatments, and differences in trial design and impact of the placebo response preclude indirect comparisons of ...
Ayda Asadizadeh Sadegh, Nina Lykkegaard Gehr, Nanna Brix Finnerup   +2 more
doaj   +1 more source

Channel Capacity of Wavelength Division Multiplexing-Based Brillouin Optical Time Domain Sensors

IEEE Photonics Journal, 2018
We propose and demonstrate a novel WDM-based Brillouin optical time domain analysis (BOTDA) sensor using Brillouin loss configuration, and theoretically analyze channel capacity of WDM-based brillouin optical time domain reflectometry (BOTDR) and BOTDA ...
Zelin Zhang, Yuangang Lu, Yunqin Zhao
doaj   +1 more source

Effectiveness and Tolerability of Topical Amitriptyline 10% Plus Lidocaine 2% Gel in Adults With Post‐Traumatic Trigeminal Neuropathic Pain: A Real‐World Evidence Study

Journal of Oral Rehabilitation, EarlyView.
A compounded amitriptyline 10% plus lidocaine 2% mucoadhesive gel was associated with substantial pain improvement and favourable tolerability in adults with post‐traumatic trigeminal neuropathic pain (PTNP). These findings support targeted mucosal delivery as a promising practical local option and a potential medication‐sparing strategy, particularly ...
Ashley Lebel, Imen Stambouli, Yves Boucher   +2 more
wiley   +1 more source

Characterization of the Pharmacokinetics and Physiological Effects of Tapentadol in Horses

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Tapentadol is a dual mechanism analgesic utilizing both μ‐opioid receptor (MOR) agonism and norepinephrine reuptake inhibition (NRI). This study evaluated the pharmacokinetics and pharmacodynamics of tapentadol as a potential analgesic with the goal of treating pain in horses.
Annabella D. Lynch, Khursheed R. Mama, Dan S. McKemie, Phillip H. Kass, Heather K. Knych   +4 more
wiley   +1 more source

Association of SSRI and SNRI use with incidence of cardiovascular events in veterans with giant cell arteritis and polymyalgia rheumatica

Frontiers in Immunology
The leading cause of death in patients with giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) is cardiovascular disease. The objective of this study was to determine whether the use of selective serotonin reuptake inhibitors (SSRI) and ...
Tianyu Zhang, Chris A. Gentry, Nicole M. Kuderer, Gary H. Lyman, Gary H. Lyman, Bernard Ng, Despina Michailidou, Despina Michailidou   +7 more
doaj   +1 more source

A Pharmacovigilance Approach for Post-Marketing in Japan Using the Japanese Adverse Drug Event Report (JADER) Database and Association Analysis.

PLoS ONE, 2016
BackgroundRapid dissemination of information regarding adverse drug reactions is a key aspect for improving pharmacovigilance. There is a possibility that unknown adverse drug reactions will become apparent through post-marketing administration ...
Masakazu Fujiwara, Yohei Kawasaki, Hiroshi Yamada   +2 more
doaj   +1 more source

Concomitant use of opioid medications with triptans or serotonergic antidepressants in US office-based physician visits

Drug, Healthcare and Patient Safety, 2018
Kyle C Molina, Kathleen A Fairman, David A Sclar Department of Pharmacy Practice, Midwestern University College of Pharmacy–Glendale, Glendale, AZ, USA Background: Opioids are not recommended for routine treatment of migraine because their benefits
Molina KC, Fairman KA, Sclar DA
doaj