Results 81 to 90 of about 18,707 (219)
Galactorrhea with antidepressants: A case series
Indian Journal of Psychiatry, 2018 Galactorrhoea is a rare but distressing, and often embarrassing adverse effects of selective serotonin reuptake inhibitors (SSRIs) treatment. Here we report three cases that developed galactorrhoea with combination of SSRIs or combination of SSRI and ...
Navratan Suthar +3 more
doaj +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders
British Journal of Pharmacology, EarlyView.Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman +3 more
wiley +1 more source
Cancer pain: current practice and emerging targets
British Journal of Pharmacology, EarlyView.Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
An Exploratory Analysis of Pharmaceutical Price Disparities and Their Implications Among Six Developed Nations [PDF]
, 2006 In our study of 43 drugs, prescription drug prices in several wealthy nations (Australia, Canada, France, Germany, and the U.K.) were much lower than in the U.S. on average, well below relative per capita GDP. There was relatively little difference among
Elizabeth DuPre +2 more
core
Journal of Oral Rehabilitation, EarlyView.A compounded amitriptyline 10% plus lidocaine 2% mucoadhesive gel was associated with substantial pain improvement and favourable tolerability in adults with post‐traumatic trigeminal neuropathic pain (PTNP). These findings support targeted mucosal delivery as a promising practical local option and a potential medication‐sparing strategy, particularly ...
Ashley Lebel +2 more
wiley +1 more source
Interference Mitigation in Large Random Wireless Networks [PDF]
, 2011 A central problem in the operation of large wireless networks is how to deal with interference -- the unwanted signals being sent by transmitters that a receiver is not interested in. This thesis looks at ways of combating such interference.
Aldridge, Matthew
core
Functional and structural connectivity of thalamic subnuclei in major depressive disorder at 7 Tesla
Psychiatry and Clinical Neurosciences, EarlyView.Aims Major depressive disorder (MDD) is widely considered to be a mood disorder characterized by altered connectivity. The thalamus plays an important role in MDD by connecting large areas of the brain. Here, we explored thalamic connectivity in MDD at the subnuclear level using ultra‐high‐field MRI.
Weijian Liu +10 more
wiley +1 more source
PAIN Reports. Neuropathic pain is a challenging chronic pain condition. Limited knowledge exists regarding the relative effectiveness of pharmacological treatments, and differences in trial design and impact of the placebo response preclude indirect comparisons of ...
Ayda Asadizadeh Sadegh +2 more
doaj +1 more source
Channel Capacity of Wavelength Division Multiplexing-Based Brillouin Optical Time Domain Sensors
IEEE Photonics Journal, 2018 We propose and demonstrate a novel WDM-based Brillouin optical time domain analysis (BOTDA) sensor using Brillouin loss configuration, and theoretically analyze channel capacity of WDM-based brillouin optical time domain reflectometry (BOTDR) and BOTDA ...
Zelin Zhang, Yuangang Lu, Yunqin Zhao
doaj +1 more source