Results 111 to 120 of about 61,991 (349)
“The Poison That Ruined the Nation”: Native American Men—Alcohol, Identity, and Traditional Healing
Alcoholism and destructive drinking patterns are serious social problems in many Native American reservation and urban communities. This qualitative study of men from a single Great Lakes reservation community examined the social, cultural, and ...
Arieahn Matamonasa-Bennett PhD
doaj +1 more source
Treatment Courts and Court-Affiliated Diversion Projects for Prostitution in the United States [PDF]
In February of 2009, staff of the Chicago Coalition for the Homeless began a dialogue with the Honorable Paul P. Biebel, Presiding Judge of Cook County Criminal Courts, regarding the possibility of a new problem-solving court specializing in prostitution
Daria Mueller
core
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Is Medieval Economic Thought ‘Ecological’? The Case of Thomas Aquinas
In a famous 1967 article, Lynn White predicted the coming climate crisis and attributed responsibility for it to the medieval conception of man and nature.
Pierre Januard
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Finding the Fit: A Review of Three Intervention Models for Working with HIV/AIDS Impacted Substance Users who are Homeless [PDF]
This report reflects research on three different models of services for people living with Human Immunodeficiency Virus (HIV) or Acquired Immunodeficiency Syndrome (AIDS) who are also low-income, substance users and are homeless or at risk of becoming ...
Amy Rynell, Maryann Mason
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Essay: Popular Modernism And The American Prose Poem: From Sherwood Anderson To Kenneth Patchen [PDF]
peer ...
Delville, Michel
core +1 more source
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source

