Results 51 to 60 of about 61,991 (349)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Sobriety and Satiety: Is NAD+ the Answer?
Antioxidants, 2020 Nicotinamide adenine dinucleotide (NAD+) is an essential pyridine nucleotide that has garnered considerable interest in the last century due to its critical role in cellular processes associated with energy production, cellular protection against stress ...
N. Braidy, Maria D Villalva, S. V. Eeden
semanticscholar +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
VLADIMIR AXIONOV’S SOCIAL ABILITIES AND ORGANIZATIONQUALITIES [PDF]
Studiul Artelor şi Culturologie: Istorie, Teorie, Practică, 2015 The purpose of the present theses was to bring out the social abilities and organization qualities of Vladimir Axionov, an educator of high professional scope.
STARŢEV ALA
doaj
SUCCESS IN DRUG COURT: THE OFFENDERS\u27 PERSPECTIVE [PDF]
, 2015 Drug Courts have demonstrated a reduction in recidivism in comparison to traditional probation programs. Prior studies have not addressed why drug courts are effective from the participants\u27 perspective.
Snell, Clete, Dr.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Liver transplantation for alcoholic liver disease: a retrospective analysis of recidivism, survival and risk factors predisposing to alcohol relapse [PDF]
, 2013 Background and study aims : Alcoholic liver disease (ALD) is the second most common indication for liver transplantation. The aim of this study was to evaluate the alcohol relapse rate and long-term survival after liver transplantation for ALD and to ...
Berrevoet, Frederik +9 more
core
Changes of frontal cortical subregion volumes in alcohol dependent individuals during early abstinence: associations with treatment outcome. [PDF]
, 2020 We previously reported that at 1-and-4 weeks of sobriety, those who relapsed after treatment demonstrated significantly smaller total frontal cortical volume than individuals who maintained abstinence for at least 12 months post treatment.
Durazzo, Timothy C, Meyerhoff, Dieter J
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Lien Social et PolitiquesLa sobriété, pierre angulaire de nombreux discours écologiques, se définit par une réduction active de sa consommation. Parce que les personnes en situation de pauvreté ont des marges de manoeuvre réduites, il leur est difficile de se conformer à l ...
Olivia Mercier
doaj +1 more source