Results 181 to 190 of about 43,731 (215)

1‐(Acetylamino)thioxanthones and Derivatives: Synthesis From 1‐Halogenothioxanthones and Biological Properties

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 30, 12 August 2026.
The conversion of 1‐halogenothioxanthones into 1‐(acetylamino) derivatives and their NaH‐mediated cyclization have been optimized. This rapid method yields thiochromeno[4,3,2‐de]quinol‐2‐ones that exhibit promising in vitro anticancer activity. Institute and/or researcher Bluesky usernames: https://bsky.app/profile/iscr‐rennes.bsky.social.
Najet Ballagha   +12 more
wiley   +1 more source

Using the suicide audit method to examine trajectories of adolescent girls following a suicide attempt in Québec, Canada: a study protocol. [PDF]

open access: yesBMJ Open
Kourgiantakis T   +7 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, Volume 20, Issue 8, Page 1963-1985, August 2026.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, Volume 20, Issue 8, Page 1905-1912, August 2026.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Expert consensus-based clinical practice guidelines for Care and weaning procedures in tracheostomized ICU patients after invasive mechanical ventilation: a joint statement by the Intensive Care Physiotherapy Society (SKR) and the French Intensive Care Society (SRLF). [PDF]

open access: yesAnn Intensive Care
Medrinal C   +24 more
europepmc   +1 more source

Transition to Adulthood Through Coaching and Empowerment in Rheumatology (TRACER): Results of a Feasibility Randomized‐Control Trial

open access: yesACR Open Rheumatology, Volume 8, Issue 8, August 2026.
Objective Health care transitions are a time of high needs for youth with chronic rheumatic conditions. Our study aimed to evaluate the feasibility of a multicenter randomized‐controlled trial implementing a virtual transition coach intervention (TCI) for youth transitioning from pediatric to adult rheumatology care.
Madison Lackie   +6 more
wiley   +1 more source

Oxygenation in acute exacerbation of interstitial lung disease:a nationwide survey. [PDF]

open access: yesSci Rep
Artaud-Macari E   +5 more
europepmc   +1 more source

Stratification by a polygenic risk score of common variation aids in Alzheimer's disease rare variant discovery

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION We utilized an Alzheimer's disease (AD) polygenic risk score (PRS) to discover associations with novel rare variants (RVs). METHODS PRSs for European ancestry (EA) participants of the Alzheimer's Disease Sequencing Project were calculated using summary statistics from a large genome‐wide association study.
Oluwatosin Olayinka   +13 more
wiley   +1 more source

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