Results 141 to 150 of about 798,697 (287)
[Review of] Alain LeRoy Locke (Jeffrey C. Stewart, ed.). Race Contacts and Interracial Relations: Lectures on the Theory and Practice of Race [PDF]
Scholars of the history of race and race relations social science should be deeply indebted to Jeffrey C. Stewart for uncovering and meticulously reconstructing these extant lectures by the philosopher better known for his later contributions to the ...
Williams, Vernon, Jr
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Communicating Resilience: A Discursive Leadership Perspective [PDF]
In this essay we challenge whether current conceptions of optimism, hope, and resilience are complete enough to account for the complexity and nuance of developing and maintaining these in practice.
Fyke, Jeremy P., Torres, David H
core +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
HIGHER EDUCATION AND SOCIETY: RUSSIA AND OTHER COUNTRIES
Higher education is an institute of excellent importance for society and its development deeply depends on public support. It’s impossible to score a success with poor finance, bad infrastructure and without legal protection.
Anatoliy I. Rakitov, Alina E. Anisimova
doaj
Integrated Care for People with Dementia-Results of a Social-Scientific Evaluation of an Established Dementia Care Model. [PDF]
Richter S.
europepmc +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Developing a Collaborative Agenda for Humanities and Social Scientific Research on Laboratory Animal Science and Welfare. [PDF]
Davies GF +41 more
europepmc +1 more source
The Social Construction of Successful Market Reforms [PDF]
The transition from socialism to capitalism has spawned a large literature on comparative policy reforms. While many sociologists using qualitative data have concluded that neo-liberal reforms led to negative outcomes, a large body of cross-national ...
David Stuckler +2 more
core
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source

