Results 111 to 120 of about 623,753 (303)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Max Weber as an excuse: Curiosities of “social philosophy” [PDF]
Социологический журнал, 2012 The article analyzes the monograph of A.B. Rakhmanov “Social Philosophy of Max Weber”, in which criticism of Weber's sociology is used as an excuse for the revivification of Marxist social utopia.
doaj
Climate change, forest conservation and science: A case study of New Zealand, 1860s-1920 [PDF]
, 2009 To most of its European settlers, New Zealand was a land blessed by Providence. A temperate climate and year-round rainfall, easy availability of land and myriad work opportunities attracted many to the new colony.
Beattie, James John
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
VertigO, 2009 This article explores how social and scientific rationalities came into play in the context of the decontamination of the Bonfol (Switzerland) industrial dumping ground, and what consequences resulted from it.
Cecchini Amaranta
doaj
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Mengungkap Kekuatan Transformasi melalui Rasionalitas serta Kritisisme
MediaThe essay deals with the power of transformation through rationality and criticism (Max Horkheimer's Dialectical Analysis of the Enlightenment). It is a review article that discusses the main topic using a literature study. According to the Dialectics of
Fildza Nardina Fitria, Theguh Saumantri
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
, 1998 A brief reconstruction of the birth, rise and ironical destiny of an almost universal expansion to other disciplines going with a dissolution within the original birthplace of the conception of an economic man, a male-only abstraction forgetful of its ...
Cremaschi, Sergio Volodia Marcello
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source