Results 111 to 120 of about 624,383 (304)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Transcendental Pragmatics and Hermeneutics [PDF]

open access: yes, 2004
: In which sense could transcendental pragmatics combined with a hermeneutical approach provide the social sciences with a critical oriented approach?
Hedberg, Petra
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Max Weber as an excuse: Curiosities of “social philosophy” [PDF]

open access: yesСоциологический журнал, 2012
The article analyzes the monograph of A.B. Rakhmanov “Social Philosophy of Max Weber”, in which criticism of Weber's sociology is used as an excuse for the revivification of Marxist social utopia.
doaj  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

\u3cem\u3eFrankenstein\u3c/em\u3e, Feminism, and Literary Theory [PDF]

open access: yes, 2003
Cave ab homine unius libri, as the Latin epigram warns us: beware the author of one book. Frankenstein has so overshadowed Mary Shelley\u27s other books in the popular imagination that many readers believe - erroneously - that she is a one-book author.
Hoeveler, Diane
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Mengungkap Kekuatan Transformasi melalui Rasionalitas serta Kritisisme

open access: yesMedia
The essay deals with the power of transformation through rationality and criticism (Max Horkheimer's Dialectical Analysis of the Enlightenment). It is a review article that discusses the main topic using a literature study. According to the Dialectics of
Fildza Nardina Fitria, Theguh Saumantri
doaj   +1 more source

Persuasion and Argument in the Malthus-Ricardo Correspondence [PDF]

open access: yes, 1998
We reconstruct the text, that is, we analyse the development of the discussion between Malthus and Ricardo both in the correspondence and in published works, paying special attention to (a) the use of methodological statements, (b) some pragmatic ...
Cremaschi, Sergio Volodia Marcello   +1 more
core  

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