Results 141 to 150 of about 624,383 (304)
, 2020 Abstract: The anti-vaccine movement has currently been widely discussed in many sectors of society, and much information is spread without a bigger problematization of its implications. In the context of school curricula, such issues are involved in debates on Science and Technology (C&T) development.
Medeiros da Fonseca, Eril, Duso, Leandro
openaire +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
مجله علمسنجی کاسپین, 2015 Background and aim: Altmetrics seeks to assess the scientific impact with new ways using data derived from the social Web. The aim of this paper aims to represent the concept, benefits, disadvantages and challenges of Altmetrics.
farahnaz naderbeygi +2 more
doaj
Jurnal Teologi TrinityDenominasi gereja-gereja di Indonesia sebagian besar disebabkan adanya perselisihan dan perpecahan dalam gereja karena faktor budaya, pandangan doktrin yang berbeda, politik kekuasaan dalam gereja, persoalan liturgika, sehingga terjadi konflik dan membuka denominasi gereja baru.
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Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Optimizing just-in-time adaptive interventions for interpersonal distress: mechanisms, prediction, and the challenge of engagement. [PDF]
Sci RepJaremba A +5 more
europepmc +1 more source