Results 61 to 70 of about 623,753 (303)

Review: Ulrike Freikamp, Matthias Leanza, Janne Mende, Stefan Müller, Peter Ullrich & Heinz-Jürgen Voß (Eds.) (2008). Kritik mit Methode? Forschungsmethoden und Gesellschaftskritik [Criticism as an Approach? Research Methods and Social Criticism]

open access: yesForum: Qualitative Social Research, 2010
The anthology "Criticism as an Approach? Research Methods and Social Criticism", edited by an interdisciplinary research team consisting of U. FREIKAMP, M. LEANZA, J. MENDE, S. MÜLLER, P. ULLRICH and H.-J.
Vanessa-Isabelle Reinwand
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Tratat de drept social internațional şi european (Nicolae Voiculescu, Maria-Beatrice Berna, Editura Universul Juridic, Bucureşti, 2019) [PDF]

open access: yesDrepturile Omului, 2019
The Treatise on International and European Social Law reviewed hereunder is an absolute novelty on the national level, and it fills a 10-year analysis gap on the European level.
Felicia Maxim
doaj  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Ethnic reasoning in social identity of Hebrews: A social-scientific study

open access: yesHTS Teologiese Studies/Theological Studies, 2017
Ethnicity reasoning offers one way of looking at social identity in the letter to the Hebrews. The context of socio-economic abuse and hardships of the audience creates a situation in which ethnicity in social identity becomes an important issue for the ...
Seth Kissi, Ernest van Eck
doaj   +1 more source

Contra Epstein, Good Explanations Predict [PDF]

open access: yes
Epstein has argued that an explanation\'s capacity to make predictions should play a minor role in its evaluation . This view contradicts centuries of scientific practice and, at least, decades of philosophy of science. We argue that the view is not only
Nicholas S. Thompson, Patrick Derr
core  

Respect as the Ethic of the Open Society [PDF]

open access: yes, 2006
Karl Popper’s description of the open society in terms of respect, rather than mere tolerance, appears to be highly relevant today. Although he never explicitly addressed the issues of multiculturalism and valuepluralism in contemporary societies ...
Gattei, Stefano
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

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