Results 61 to 70 of about 33,067 (254)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Verbum et Ecclesia, 2001 The life of modern people evolves around economics and all that goes with it, such as labour, production, consumption and possessions. These things do not only motivate many peoples' behaviour, but claim most of their energy and time. Therefore, the organising principle of life of people today is instrumental mastery - the individual's ability to ...
openaire +3 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Social Criticism Da’wah Through Visual Works of @Terasdakwah During the COVID-19 Pandemic
Kalijaga Journal of CommunicationThis study aims to analyze the preaching message containing social criticism on the Instagram account @terasdakwah through a semiotic approach. The @terasdakwah account is a digital platform that actively spreads preaching content in a creative style ...
Farkhan Al Faiz, Akhmad Rifa'i
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
HTS Teologiese Studies/Theological Studies, 2013 This article presents a social-scientific and realistic interpretation of the parable of the Feast. The characteristics of a pre-industrial city are used to determine the realism of the parable.
Ernest van Eck
doaj
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Les fonctions de la critique dans la sociologie de Pierre Bourdieu
AstérionThe aim of this article is to restore the complexity and multiplicity of the functions of critique in Pierre Bourdieu’s sociology. The first function is a theoretical and scientific one that allows a Bachelardian-type of epistemological breakdown to be ...
Claude Gautier
doaj +1 more source