Results 71 to 80 of about 623,753 (303)

La responsabilité sociologique : retour sur l’entreprise critique de Pierre Bourdieu

open access: yesRecherches Sociologiques et Anthropologiques, 2005
Bourdieu speaks of a two-levelled societal role of the sociologist. Firstly, thanks to its scientific quality, sociological work can make things more supportable by pointing out the fundamental laws of society.
Mathieu Hilgers
doaj   +1 more source

The Role of Truth in Psychological Science [PDF]

open access: yes, 2018
In a recent paper, Haig and Borsboom explore the relevance of the theory of truth for psychological science. Although they conclude that correspondence theories of truth are best suited to offer the resources for making sense of scientific practice, they
Asay, Jamin
core   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Resente Matteusnavorsing in Suid-Afrika

open access: yesHTS Teologiese Studies/Theological Studies, 1994
Recent Matthean-research in South Africa This article deals with recent developments in Matthean research, mostly by members of the New Testament Society of South Africa.
H. J.B. Combrink
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Marx’s Theory of World History Explained: Basic Connotations and Contemporary Context

open access: yesContemporary Social Sciences, 2022
Marx’s theory of world history is an important part of his materialist conception of history (i.e., historical materialism). Marx and Engels summarized the evolution of social history and the laws behind it based on their observations and analyses of ...
Shuai Qian
doaj  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Science democratised = expertise decommissioned [PDF]

open access: yes, 2007
Science and expertise have been antithetical forms of knowledge in both the ancient and the modern world, but they appear identical in today’s postmodern world, especially in Science & Technology Studies (STS) literature. The ancient Athenians associated
Fuller, Steve
core   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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