Results 91 to 100 of about 16,123,395 (250)
, 2014 In this report we start by setting the context for our scoping analysis of the role and functions of middle managers in Scotland's social services. Within this section, we discuss the challenge of identifying ‘who is a middle manager' and whether ...
Patterson, Frances, George, Carol
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
SOCIAL WORK: Putting together the broken pieces of our lives
, 2018 The journal has an eclectic mix of articles, but all offer the opportunity to reflect on the varied aspects of social work ...
Browne, Frank +1 more
core
Propuestas Críticas en Trabajo Social, 2021 Propuestas Críticas en Trabajo Social - Critical Proposals in Social Work
doaj
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
[Embargo] PHOS - Political Hostility Scale (tssq26_7)
The Social Study administered Deliberative assemblies (tssq26_2) questionnaire on behalf of Jeremy Dodeigne (UNamur) between 31-03-2026 and 24-05-2026. The collected data are stored in this Dataverse with strictly restricted access. Only the designated
The Social Study (TSS)
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source