Results 61 to 70 of about 9,772,075 (262)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Documento de Alistamiento - Ruta de Innovación Social.
, 2021 El documento de Alistamiento de la RUTA de Innovación Social tiene como objetivo consolidar y resumir la información generada en la etapa Alistar; referente a la situación problemática y a los acuerdos realizados entre los socios que conformarán el ...
Parque Científico de Innovación Social - PCIS
core
Sociality in the Social. Post-Sociality as an Opportunity
Ideas and IdealsThe article substantiates the distinction between social and sociality as two levels of social ontology. The concept of the invariant of sociality is introduced to denote the ability of a set of active agents of natural or artifi cial origin to form a stable homogeneous or heterogeneous unity by orienting each agent to the coordination and coordination
openaire +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Los Angeles County Social Survey, 2002 (LACSS)
The Los Angeles County Social Survey (LACSS) continues the Los Angeles Metropolitan Area Studies (LAMAS) and the Southern California Social Surveys (SCSS).
University of California, Los Angeles. Institute for Social Science Research.
core +1 more source
The Ouro Preto Declaration: Creation of the Latin American Social Medicine Association (1984)
, 2009 Those signing below, attendees of the II Latin American Seminar on Social Medicine, have decided to establish the Latin American Association of Social ...
Social Medicine Association, Latin American +1 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Social-emotional Skills and Health in Social Education [PDF]
, 2017 L’objectiu d’aquest article és, d’una banda, analitzar la relació existent entre educació social i educació per a la salut, posant-les, totes dues, en el marc de la contribució al benestar biopsicosocial de les persones, en el qual les competències ...
López, Paco
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source