Results 71 to 80 of about 12,529,564 (274)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Factors affecting external information-seeking behavior of a public projects
Journal of Human Environmental Studies, 2017 This study focused on the factors affecting the external information-seeking behavior related to public projects. We hypothesized that when people had the cognition that the result of an opinion expression could affect the acceptance decision on a public
Kyosuke Ohana, Hiroe Maeda
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Journal of Human Environmental Studies, 2016 This study examined the difference of information seeking behaviour depending on situations when people judge acceptance of a public project. It was confirmed by a questionnaire experiment.
Kyosuke Ohana, Satoshi Fujii
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Using social norms to reduce men's rape proclivity: Perceived rape myth acceptance of out-groups may be more influential than that of in-groups. [PDF]
, 2010 Feedback about a reference group's rape myth acceptance (RMA) has been shown to affect men's rape proclivity (Bohner, Siebler, & Schmelcher, Personality and Social Psychology Bulletin, 32, 286–297, 2006). In two experiments with male university students (
G. Tendayi Viki +8 more
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
The Relationship between Attitude to Social Vulnerability of Women Heads of Households with Critical Thinking and Social Acceptance: The Mediating Role of Self-esteem [PDF]
مطالعات اجتماعی روانشناختی زنانFemale-headed households face multiple challenges due to simultaneously fulfilling paternal and maternal roles. The present study was conducted with the aim of investigating the structural relationships of Attitude to social vulnerability based on ...
Fatemeh Jadidi +3 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source