Results 131 to 140 of about 1,021,052 (261)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

The intersection of structural social factors, loneliness, and social activity in individuals with psychotic disorders. [PDF]

Schizophr Res
McBride LE, Gentry MM, Pinkham AE, Granholm E, Harvey PD, Palmer BW, Lee EE, Depp CA.   +7 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Impact of video game addiction on social interaction: An observational review examining loneliness, social anxiety, and social activity. [PDF]

World J Psychiatry
Byeon H.
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

The Effect of Social Activity Program on the Autonomy and Life Engagement of Nursing Home Residents: A One-Group Pretest-Posttest Study. [PDF]

Florence Nightingale J Nurs
Küçük A, Emiroğlu ON.
europepmc   +1 more source

Social activity diversity as a lifestyle factor to alleviate loneliness and chronic pain. [PDF]

J Psychosom Res, 2023
Lee S, Small BJ, Cawthon PM, Stone KL, Almeida DM.   +4 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

A Mediterranean diet improves endothelial function in men and women over 65 years: Results from the MedLey study

Journal of Nutrition & Intermediary Metabolism, 2017
C.R. Davis, K.J. Murphy, J.M. Hodgson, J. Bryan, R.J. Woodman, C. Wilson   +5 more
doaj   +1 more source

Neighborhood bonding and bridging social capital, social activity participation, and short-term cognitive variability in later life. [PDF]

J Gerontol B Psychol Sci Soc Sci
Hyun J, Cerino ES, Katz MJ, Lovasi G, Lipton RB, Sliwinski MJ.   +5 more
europepmc   +1 more source