Results 161 to 170 of about 19,124,510 (306)

Social activity recognition based on probabilistic merging of skeleton features with proximity priors from RGB-D data

IEEE/RJS International Conference on Intelligent RObots and Systems, 2016
Claudio Coppola, D. Faria, U. Nunes, N. Bellotto   +3 more
semanticscholar   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Social activity as a mediator between childhood adversity and depressive symptoms in middle-aged and older Chinese adults. [PDF]

Front Psychiatry
Wu P, Ding J, Jin H, Zhang J, Greenshaw AJ, Liang S.   +5 more
europepmc   +1 more source

Perceived Control and Social Activity in Midlife and Older Age: A Reciprocal Association? Findings From the German Ageing Survey

The journals of gerontology. Series B, Psychological sciences and social sciences, 2016
R. Curtis, O. Huxhold, T. Windsor
semanticscholar   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Balancing Infection Risks and Residents Social Activity Preferences: Nursing Home Staff Risk Perceptions. [PDF]

Gerontologist
McClean M, Akter N, Kowalchik KH, Mogle J, Kitt-Lewis EA, Paudel A, Jones JR, Carpenter JG, Behrens LL.   +8 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Determinants of Social Activity Among Geriatric Patients in Northern Romania: A Cross-Sectional Study. [PDF]

J Clin Med
Donca V, Grad DA, Ungureanu MI, Bodolea C, Hirişcău EI, Avram L.   +5 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

In your 20s it's quantity, in your 30s it's quality: the prognostic value of social activity across 30 years of adulthood.

Psychology and Aging, 2015
Cheryl L. Carmichael, H. Reis, P. Duberstein   +2 more
semanticscholar   +1 more source