Results 71 to 80 of about 19,124,510 (306)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Course of neuropsychological health in post-COVID patients differs 6 and 12 months after inpatient rehabilitation

open access: yesFrontiers in Psychiatry
BackgroundRehabilitation is an effective and feasible approach for post-COVID patients to improve mental health and cognitive complaints. However, knowledge regarding the long-term impact of rehabilitation on neuropsychological health of these patients ...
Katrin Müller   +5 more
doaj   +1 more source

Long-term outcomes (2 and 3.5 years post-intervention) of the INFANT early childhood intervention to improve health behaviors and reduce obesity: cluster randomised controlled trial follow-up

open access: yesInternational Journal of Behavioral Nutrition and Physical Activity, 2020
Background The few health behavior interventions commencing in infancy have shown promising effects. Greater insight into their longer-term benefits is required.
Kylie D. Hesketh   +9 more
doaj   +1 more source

Effects of social activity on health-related quality of life according to age and gender: an observational study

open access: yesHealth and Quality of Life Outcomes, 2015
BackgroundThe aim of this study was to examine the relationship between types and amount of social activity and health-related quality of life according to gender and age group.MethodsThis study used data from the Community Health Survey (CHS), which was
H. Park   +5 more
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Journey Into Social Activism : Qualitative Approaches [PDF]

open access: yes, 2017
Academic study of social activism and social movements has become increasingly prevalent over the years; this is due in large part to the fact that activists have captured public imagination and gained substantial influence in political discourse. For instance, Occupy Wall Street activists, Tea Party activists, and activists affiliated with the Arab ...
openaire   +3 more sources

Locations that Support Social Activity Participation of the Aging Population

open access: yesInternational Journal of Environmental Research and Public Health, 2015
Social activities are an important aspect of health and quality of life of the aging population. They are key elements in the prevention of loneliness.
P. van den Berg   +3 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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