Results 91 to 100 of about 1,021,052 (261)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Determination of 3-hydroxyanthranilic acid in the sweat of healthy older adults

Scientific Reports
3-Hydroxyanthranillic acid (3HAA) is one of the key metabolites from the tryptophan (TRP) metabolism pathway and is associated with aging, age-associated diseases, and healthy lifespan extension.
Kanlaya Prapainop Katewongsa, Preeyanuch Manohong, Yaowapa Trangan, Rungrat Palakai, Sirinapa Mysook, Thitirat Mantim, Pairoj Saonuam, Piyawat Katewongsa   +7 more
doaj   +1 more source

The Relationship Between Organization in Time, Executive Functions, and Quality of Life in Adult ADHD

Brain Sciences
Background/Objectives. Despite the importance of organization-in-time ability for adults’ daily performance, knowledge about this ability in adults with attention-deficit/hyperactivity disorder (ADHD) remains limited.
Nufar Grinblat, Sara Rosenblum
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Canicross Pilot Programme: Basic Considerations for Its Implementation as an Extracurricular Sports Activity

Education Sciences
Canicross is a sport that consists of running while being pulled by a dog in a natural environment. Due to the benefits to health and well-being that it brings to the people and dogs that practise it, this sport could be implemented as an animal-assisted
Xabier Gonzalez-Santamaria, Erika Borrajo, Eneko Sanchez-Mencia, Maite Aurrekoetxea-Casaus   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A Fully Replicable Exercise Program for Individuals with Sleep-Disordered Breathing: Protocol Design and Training Load Monitoring

Journal of Functional Morphology and Kinesiology
Objectives. The objectives of this study were (i) to design in detail an exercise program for individuals with sleep-disordered breathing (SDB) that would be reproducible, and (ii) to present a system for monitoring training load (volume × intensity ...
Jose M. Saavedra, Katrin Y. Fridgeirsdottir, Conor J. Murphy, Harald Hrubos-Strøm, Erna S. Arnardottir   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Effectiveness of Intervention Strategies to Increase Adolescents’ Physical Activity and Reduce Sedentary Time in Secondary School Settings, Including Factors Related to Implementation: A Systematic Review and Meta-Analysis

Sports Medicine - Open
Background Globally, just one in five adolescents meet physical activity guidelines and three-quarters of the school day is spent sitting. It is unclear which types of school-based interventions strategies increase physical activity and reduce sedentary ...
Ana María Contardo Ayala, Kate Parker, Emiliano Mazzoli, Natalie Lander, Nicola D. Ridgers, Anna Timperio, David R. Lubans, Gavin Abbott, Harriet Koorts, Jo Salmon   +9 more
doaj   +1 more source