Results 71 to 80 of about 1,770,192 (303)

СОЦИАЛЬНАЯ АДАПТАЦИЯ УЧАЩЕЙСЯ МОЛОДЕЖИ КОРЕННЫХ МАЛОЧИСЛЕННЫХ НАРОДОВ СЕВЕРА В ГОРОДСКИХ УСЛОВИЯХ

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2015
Предмет исследования: особенности социальной адаптации учащейся в городских условиях молодежи коренных малочисленных народов Севера Республики Саха (Якутия).Цель исследования: выявить особенности социальной адаптации учащейся молодежи коренных ...
Alena Georgievna Tomaska
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Production and use of rapid responses during the COVID-19 pandemic in Quebec (Canada): perspectives from evidence synthesis producers and decision makers

open access: yesHealth Research Policy and Systems
Background The COVID-19 pandemic has required evidence to be made available more rapidly than usual, in order to meet the needs of decision makers in a timely manner.
Esther McSween-Cadieux   +10 more
doaj   +1 more source

Falls and loneliness among Chinese older adults: evidence from a nationally representative longitudinal study

open access: yesFrontiers in Public Health
BackgroundFalls and loneliness are both common during older adulthood and detrimental to older adults’ health. However, it remains unclear whether and how falls may be longitudinally related to loneliness among older adults, despite some cross-sectional ...
Zhiqiang Yu, Meng Jiang, Yueyun Zhang
doaj   +1 more source

TRANSFORMATION OF LIFESTYLE NORTHERN FAMILIES: SOCIAL ADAPTATION TO CHANGING CONDITIONS

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2015
The nomadic lifestyle of northern people in the past three hundred years has undergone a radical transformation under the influence of Russian state policy.
Tatjana Nikolaevna Konstantinova
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Predicting the Trend of Well-Being in Germany: How Much Do Comparisons, Adaptation and Sociability Matter? [PDF]

open access: yes
Using longitudinal data on households living in Germany, we quantify what part of the change in subjective well-being observed over the last two decades is predicted by changes in variables which typically show strong cross-sectional correlation with ...
BARTOLINI Stefano   +2 more
core   +4 more sources

Coexistence of Social Norms based on In- and Out-group Interactions [PDF]

open access: yes, 2007
The question how social norms can emerge from microscopic interactions between individuals is a key problem in social sciences to explain collective behavior. In this paper we propose an agent-based model to show that randomly distributed social behavior
Fent, Thomas   +2 more
core   +2 more sources

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