Results 101 to 110 of about 13,017,750 (257)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Technology-facilitated violence against child welfare workers: A qualitative analysis

Child Protection and Practice
Background: Advances in technology have influenced the provision of child welfare services in a variety of ways creating both new opportunities to improve services and new risks, including the risk of technology-facilitated violence (TFV) against workers.
Cheryl Regehr, Faye Mishna, Danielle Billard, Barbara Fallon, Jeffrey Schiffer, Rachael Lefebvre   +5 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Institutions, Trade, and Social Cohesion in Fragile States [PDF]

This paper examines the contribution of institutions, social cohesion, and trade to development (per-capita income) with emphasis on fragile states in Africa. Results from GMM estimations suggest that political institutions, openness to trade, and social
Mina Baliamoune-Lutz
core  

Learning from the past: a scoping review of hospital disaster preparedness assessment

BMC Emergency Medicine
Background Despite the recognized importance of hospital disaster preparedness (HDP), efforts to improve it have been limited. Improvement in HDP will need an in-depth comprehension of the prevailing gaps in addition to evidence of the best practices ...
Prinka Singh, Sujan Sapkota, Nebil Achour, Luca Ragazzoni, Hamdi Lamine   +4 more
doaj   +1 more source

Life skills workshop impact: enhancing classroom adaptation for at-risk primary students in Chile

Frontiers in Psychology
BackgroundDifficulties adjustment to school in childhood are one of the risk factors for developing mental health problems. When school adjustment problems arise, they tend to persist over time; therefore, early identification and intervention can help ...
Alejandro Cuadra-Peralta, Constanza Beatriz Veloso-Besio, Camila Chamorro, Michelle Ibergarai-Pérez, Lorena Gallardo-Peralta, Lorena Gallardo-Peralta   +5 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

A REALIDADE EMPÍRICA DO SISTEMA ÚNICO DE ASSISTÊNCIA SOCIAL (SUAS) NAS REGIÕES NORTE E NORDESTE

Revista de Políticas Públicas, 2020
This article presents results of a study on the Social Aid Policy and implementation of SUAS. It contains bibliographic, documental and empirical researches developed in Pará, Maranhão and Ceará States and in 18 municipalities of those States, situated ...
Maria Ozanira da Silva e Silva, Leila Passos Bezerra, Annova Miriam Ferreira Carneiro, Maria Eunice Ferreira Damasceno Pereira, Maria Antonia Cardoso Nascimento   +4 more
doaj  

Geografia social da AIDS no Brasil The social geography of AIDS in Brazil

Revista de Saúde Pública, 1995
São divulgados os primeiros resultados da avaliação da dinâmica da epidemia da AIDS no Brasil através de técnicas de análise da distribuição espacial. São revisadas questões metodológicas, apontando as dificuldades de estabelecer regiões geográficas homogêneas no Brasil.
Francisco Inácio Bastos, Christovam Barcellos   +1 more
openaire   +1 more source