Results 91 to 100 of about 1,495,220 (334)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The FDA's Diverse and Dynamic Activities in the Social and Behavioral Sciences: Advancing and Supporting Health Equity. [PDF]

J Prim Care Community Health, 2021
Lee C, McLean MJ, Huang CJ, Nguyen Zarndt A, Aikin KJ, Rausch P, Cohen BR, Delahanty J, Sholly DM, Slavit WI, Carlton ED.   +10 more
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Development will (try to) find its way: a qualitative study of Chilean adolescent mental health during and after lockdown

Child and Adolescent Psychiatry and Mental Health
Background The COVID-19 pandemic has had a well-evidenced impact on adolescents, who are especially sensitive to pandemic disruptions given the critical role of socialization in their development.
Camila Espinoza, Florencia Canessa, Shelley van der Veek, Lenneke Alink, Anja van der Voort   +4 more
doaj   +1 more source

SOCIO WORLD SOCIAL RESEARCH & BEHAVIORAL SCIENCES

, 2022
Namig Isazade
openalex   +1 more source

CSBS Statements, v15, 2013 [PDF]

, 2013
Inside This Issue: -- From the Desk of the Dean-- Stephen Quirk-- CSBS faculty provides social science research support to YESS-- CSBS alumna served as YESS intern and found her place-- Quirk family leaves legacy in CSBS-- A Young Hopeful-- We need to ...
University of Northern Iowa. College of Social and Behavioral Sciences.
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

CSBS Kudos, Fall 2012 [PDF]

, 2012
Inside This Issue: -- New Year, New Faces-- New CSBS Faculty-- Meet Our New Constituent Development Officer-- Domestic Violence Awareness Month-- Around CSBS-- Faculty & Staff Kudos-- 2012 Summer Fellowship Recipients-- Award-winning Faculty-- Around the
University of Northern Iowa. College of Social and Behavioral Sciences.
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

CSBS Kudos, Spring 2018 [PDF]

, 2018
Inside This Issue: -- Faculty Accolades-- Retirees-- Departmental News-- Student Spotlight-- Alumni Highlightshttps://scholarworks.uni.edu/csbskudos/1023/thumbnail ...
University of Northern Iowa. College of Social and Behavioral Sciences.
core   +1 more source