Results 91 to 100 of about 1,482,184 (378)

Editorial: Critical social and behavioral sciences perspectives on ending the HIV epidemic. [PDF]

Curr Opin HIV AIDS, 2022
Auerbach JD, Dubé K.
europepmc   +1 more source

CSBS Statements, v23, 2021 [PDF]

, 2021
In This Issue: From the Dean --- 4Shining Bright --- 5Mapping Connections --- 8Saving Faith --- 10Coping with COVID --- 12Addressing Adversity --- 14College News --- 16Student Spotlight --- 21Alumni Highlights --- 26Class Notes --- 32Annual Giving ...
University of Northern Iowa. College of Social and Behavioral Sciences.
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

The FDA's Diverse and Dynamic Activities in the Social and Behavioral Sciences: Advancing and Supporting Health Equity. [PDF]

J Prim Care Community Health, 2021
Lee C, McLean MJ, Huang CJ, Nguyen Zarndt A, Aikin KJ, Rausch P, Cohen BR, Delahanty J, Sholly DM, Slavit WI, Carlton ED.   +10 more
europepmc   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Development will (try to) find its way: a qualitative study of Chilean adolescent mental health during and after lockdown

Child and Adolescent Psychiatry and Mental Health
Background The COVID-19 pandemic has had a well-evidenced impact on adolescents, who are especially sensitive to pandemic disruptions given the critical role of socialization in their development.
Camila Espinoza, Florencia Canessa, Shelley van der Veek, Lenneke Alink, Anja van der Voort   +4 more
doaj   +1 more source

Social disparities in body mass index (BMI) trajectories among Chinese adults in 1991–2011

International Journal for Equity in Health, 2017
Background Obesity is a serious public health problem in China. The relationship between obesity and socio-economic status (SES) is changing and affected by uncertainty, particularly, in developing countries.
Changchun Fang, Ying Liang
doaj   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Toward some circuitry of ethical robots or an observational science of the genesis of social evaluation in the mind-like behavior of artifacts [PDF]

, 1956
Warren S. McCulloch
openalex   +1 more source