Results 111 to 120 of about 1,482,184 (378)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Targets Are Not Believed [PDF]

open access: yes, 2015
The interpersonal challenges that workplace bullying introduce are discussed in terms of reducing the reputation of the target within the workplace and the veracity of their claims.
Kircher, Jan
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Targets Can Mutate into the Bully [PDF]

open access: yes, 2015
The phenomenon of targets turning into bullies occurs in workplace cultures that maintain the status quo of aggression. Targets may become bullies to reclaim the power they once had or regain control of their professional life.
Kircher, Jan
core   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

An Approach to the Islamization of Social and Behavioral Sciences

open access: yesAmerican Journal of Islam and Society, 1989
AbstractIn this paper I have tried to argue that the two widely used paradigmsof Individualism in Western social science, and Collectivism in Soviet socialscience, are not appropriate for Islamic social science on account of thesecularism (disregard of revelation) of the former and the "scientific atheism"of the latter.
openaire   +2 more sources

Am I Being Bullied at Work? [PDF]

open access: yes, 2015
Challenges to identifying oneself as a target of workplace bullying are discussed. Strategies such as maintaining a log and recording events are presented as the first step to remediating workplace ...
Kircher, Jan
core   +1 more source

The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy