Results 41 to 50 of about 2,967,604 (309)

The influence of organizational factors on the attitudes of residential care staff toward the sexuality of residents with dementia

open access: yesBMC Geriatrics, 2019
Background The attitudes of care staff toward the sexuality of residents with dementia they care for is assumed to influence the residents’ expression of their sexuality in the way they want.
Tineke S. M. Roelofs   +3 more
doaj   +1 more source

Racism in Football in Portugal: Perceptions of Multiple Actors

open access: yesSocial Sciences, 2023
The present paper aims to analyze and understand, from an intersectional point of view, the extent and the characteristics of racism in football in Portugal, based on the perspectives of football fans, coaches, amateur players, professional players ...
Sofia Neves   +3 more
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Shared social identity and media transmission of trauma

open access: yesScientific Reports, 2023
When an individual or group trauma becomes a shared public experience through widespread media coverage (e.g., mass violence, being publicly outed), sharing a social identity with a targeted individual or group of victims may amplify feelings of personal
Daniel P. Relihan   +3 more
doaj   +1 more source

Boltzmann-like and Boltzmann-Fokker-Planck Equations as a Foundation of Behavioral Models [PDF]

open access: yesPhysica A 196, 546-573 (1993), 1998
It is shown, that the Boltzmann-like equations allow the formulation of a very general model for behavioral changes. This model takes into account spontaneous (or externally induced) behavioral changes and behavioral changes by pair interactions. As most important social pair interactions imitative and avoidance processes are distinguished.
arxiv   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Perceived Stress and Burden of Care in Elderly Caregivers: The Moderating Role of Resilience

open access: yesSālmand, 2022
Objectives This study aimed to investigate the moderating role of resilience in the association between perceived stress and the burden of care among elderly caregivers at nursing homes in Tehran in 2016.
Mahsa Jafari   +3 more
doaj  

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