Results 61 to 70 of about 59,967 (258)

Better integrated due to a German partner?: an analysis of differences in the integration of foreigners in intra- and inter-ethnic partnerships in Germany

Revista Obets, 2008
This paper analyses differences in the integration of foreigners living in intra- and inter-ethnic partnerships in Germany. According to social distance theory, it is assumed that migrants living in an inter-ethnic partnership should be better integrated
Nina Rother
doaj   +1 more source

Embracing Partnership for Social Transformation and the Realization of Human Rights: A Pathway to Ending Female Genital Mutilation, Marginalization of Women in Political Leadership, and Other Harmful Practices Amongst the Abagusii of Kenya

Interdisciplinary Journal of Partnership Studies, 2020
Utilizing the Abagusii community of Southwestern Kenya as a case study, the author explores how patriarchy, a social system that is embedded in a domination social configuration (Eisler, 2007), is fertile ground for several practices which violate girls’
Kerubo Abuya
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The Impact Of Social Partnership On The Environment

Journal of Economic Development, Environment and People, 2016
The multidimensional social problems that everyone seeks to remedy them are very complex and no actor can confront them on their own. So the different parties have to work together by creating relations of partnerships.
Mariem Kchaich Ep Chedli
doaj  

The Tulul Al-Baqarat and Eduu Projects : Archaeological Research , Education and Cultural Heritage Enhancement

مجلة الآداب, 2018
The present paper stems from the research activities carried out within the framework of EU funded project "EDUU - Educational and Cultural Heritage Enhancement for Social Cohesion in Iraq" (EuropeAid CSO-LA/2016/382-631).
Carlo Lippolis, Jacopo Bruno, Eleonora Quirico, Ali Taha, Hasinean Mohammed, Haydar Taha   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Change in labor culture within economic institutions and consolidating the principle of the Algerian -Turkish partnership

Sociedad & Tecnología
Labor culture is a strategic factor in the performance of economic institutions, as it influences workers’ behaviors, values, and practices. In Algeria, the transition toward a market economy and the establishment of partnerships with foreign actors ...
Darmichia Lamia
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source