Results 111 to 120 of about 25,612 (298)

Modeling Social Annotation

open access: yes, 2010
Collaborative tagging systems, such as Delicious, CiteULike , and others, allow users to annotate resources, for example, Web pages or scientific papers, with descriptive labels called tags ...
Anon Plangprasopchok, Kristina Lerman
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

A Comprehensive Review of Facial Beauty Prediction Using Multi-task Learning and Facial Attributes

open access: yesARO-The Scientific Journal of Koya University
Beauty multi-task prediction from facial attributes is a multidisciplinary challenge at the intersection of computer vision, machine learning, and psychology.
Ali H. Ibrahem, Adnan M. Abdulazeez
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Understanding domestic energy consumption through interactive visualisation: a field study

open access: yes, 2012
Motivated by the need to better manage energy demand in the home, in this paper we advocate the integration into Ubicomp systems of interactive energy consumption visualisations, that allow users to engage with and understand their consumption data ...
Costanza, Enrico   +8 more
core   +1 more source

Implementing agents for a collaborative online learning environment

open access: yesJournal of Computer Science and Technology, 2004
This paper discusses the main lines used to model intelligent agents that will operate in a Collaborative Online Learning Environment-COLE. The aim of COLE is to evaluate the contribution that Information Technology and Multiagent Systems can bring to ...
Hilton José Silva de Azevedo   +3 more
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Educational use of Social Annotation Systems for Peer Feedback [Elektronisk resurs]

open access: yes, 2015
Social annotation systems provide a way for several students to annotate shared documents in an online environment (Novak, Razzouk & Johnson, 2012). We have for a number of years used social annotation systems in order to allow students to comment on
Pargman, Daniel,, Hedin, Björn,
core  

Workflow-based architecture for collaborative video annotation

open access: yes, 2022
S.33-42In video annotation research, the support of the video annotation workflow has been taken little into account, especially concerning collaborative use cases.
Hollender, Nina   +2 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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