Results 91 to 100 of about 25,612 (298)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Learning visual contexts for image annotation from Flickr groups [PDF]

, 2011
We present an extension of automatic image annotation that takes the context of a picture into account. Our core assumption is that users do not only provide individual images to be tagged, but group their pictures into batches (e.g., all snapshots taken
Ulges, A., Worring, M.; id_orcid, Adrian Ulges, Thomas Breuel, Worring, M., Breuel, T., Marcel Worring   +6 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

How to Organize the Annotation Systems in Human-Computer Environment: Study, Classification and Observations

, 2015
International audienceThe practice of annotation is a secular and omnipresent activity. We find the annotation in several areas such as learning, semantic web, social networks, digital library, bioinformatics, etc.
Mazhoud, Omar, Kacem, Ahmed,, Omheni, Nizar, Omar Mazhoud, Kacem, Ahmed, Hadj, Kalboussi, Anis, Nizar Omheni, Ahmed Hadj Kacem, Anis Kalboussi   +8 more
core   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Tagging the Bard : Evaluating the Accuracy of a Modern POS Tagger on Early Modern English Corpora [PDF]

, 2007
In this paper we focus on automatic part-of-speech (POS) annotation, in the context of historical English texts. Techniques that were originally developed for modern English have been applied to numerous other languages over recent years.
Baron, Alistair, Rayson, Paul, Archer, Dawn, Archer, DE, Smith, Nicholas, Baron, A, Culpeper, J, Culpeper, Jonathan, Rayson, P, Smith, N   +9 more
core  

SymGRASS: a database of sugarcane orthologous genes involved in arbuscular mycorrhiza and root nodule symbiosis : from Seventh International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, (CIBB 2010), Palermo, Italy, 16 - 18 September 2010 [PDF]

, 2013
Background: The rationale for gathering information from plants procuring nitrogen through symbiotic interactions controlled by a common genetic program for a sustainable biofuel production is the high energy demanding application of synthetic nitrogen ...
Horres, Ralf, Ederson Kido, Kido, Ederson Akio, Roberta Lane de Oliveira Silva, Nicolas Krezdorn, Benko-Iseppon, Ana Maria, Kahl, Günter, Lane de Oliveira Silva, Roberta, Winter, Peter, Ralf Horres, da Mota Soares Cavalcanti, Nina, Belarmino, Luis Carlos, Luis Belarmino, Nina da Mota Soares Cavalcanti, Ana Benko-Iseppon, Krezdorn, Nicolas, Peter Winter, Günter Kahl   +17 more
core   +1 more source

Method for annotating dialogue value priority based on Zero-Shot Chain-of-Thought

工程科学学报
Value priority recognition is a fundamental task in computational linguistics that focuses on discerning and categorizing the implicit hierarchical structure of human values manifested within textual expressions.
Zhiqiang MA, Jia LIU, Xin LI, Kuibo WANG, Yixing LIU, Haoran YE   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source