Results 71 to 80 of about 25,612 (298)
PLoS Computational Biology, 2020 High-throughput sequencing has become ubiquitous in biomedical sciences. As new technologies emerge and sequencing costs decline, the diversity and volume of available data increases exponentially, and successfully navigating the data becomes more ...
Christopher A Lavender +3 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Bridging the gap between social tagging and semantic annotation: E.D. the Entity Describer
, 2007 Semantic annotation enables the development of efficient computational methods for analyzing and interacting with information, thus maximizing its value.
Benjamin M. Good +2 more
core
SPEAR: spamming-resistant expertise analysis and ranking in collaborative tagging systems [PDF]
, 2011 In this article, we discuss the notions of experts and expertise in resource discovery in the context of collaborative tagging systems. We propose that the level of expertise of a user with respect to a particular topic is mainly determined by two ...
Noll, Michael G. +11 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Retrieval and Annotation of Music Using Latent Semantic Models
, 2012 PhDThis thesis investigates the use of latent semantic models for annotation and retrieval from collections of musical audio tracks. In particular latent semantic analysis (LSA) and aspect models (or probabilistic latent semantic analysis, pLSA) are ...
Levy, Mark
core
Journal of Web Semantics, 2017 Modern Web search engines still have many limitations: search terms are not disambiguated, search terms in one query can't be in dierent languages, the retrieved media items have to be in the same language as the search terms and search results are not integrated across a live stream of dierent media channels, including TV, online news and social media.
Lei Zhang 0034 +5 more
openaire +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Machine Learning and Knowledge ExtractionAutomatic Face Emotion Recognition (FER) technologies have become widespread in various applications, including surveillance, human–computer interaction, and health care. However, these systems are built on the basis of controversial psychological models
Martina Mattioli, Federico Cabitza
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source