Results 151 to 160 of about 1,897,449 (352)
Social anxiety and loneliness among older adults: a moderated mediation model
BMC Public HealthBackground Few studies have clarified the mechanisms linking social anxiety and loneliness in older populations. The study aimed to explore how social network mediate the relationship between social anxiety and loneliness in older adults, with perceived ...
Shuting Sun +8 more
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Frontiers in PsychologyBackgroundSocial anxiety has consistently emerged as a prominent manifestation of mental health issues among college students. Though the relationship between upward social comparison and social anxiety has been extensively addressed in previous ...
Lijuan Xu, Li Li
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Advanced Science, EarlyView.The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang +15 more
wiley +1 more source
Acta PsychologicaThis study examines the impact of body appreciation on social anxiety among college students, focusing on the mediating role of social suspiciousness and the moderating role of self-congruency in the relationship between body appreciation and social ...
Jinwei Zhu +4 more
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Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors
Advanced Science, EarlyView.Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen +8 more
wiley +1 more source
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023 Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei +4 more
wiley +1 more source
BuildingsAs mental health issues become increasingly prominent, social anxiety is prevalent among university students and significantly affects their social behaviors and environmental preferences.
Lan Wang, Xia Zhang, Aolin Xie
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Measurement invariance of the Social Phobia and Anxiety Inventory
, 2012 Brian E. Bunnell +2 more
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Depression and anxiety in social media: Jordan case study
, 2023 Issam AlHadid +7 more
openalex +1 more source